Evidence map›Paper›PMID 29289466›Full record

ArticleJournal of the American Society of Hypertension : JASH2018

Angiotensin II type 2 receptor inhibits expression and function of insulin receptor in rat renal proximal tubule cells.

Yang Yang, Caiyu Chen, Chunjiang Fu, Zaicheng Xu, Cong Lan, Yongchun Zeng, Zhi Chen, Pedro A Jose, Ye Zhang, Chunyu Zeng

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Society of Hypertension : JASH, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Molecules (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Yang YangDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Disease Clinical Research Center, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China.
Caiyu ChenDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Disease Clinical Research Center, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China.
Chunjiang FuDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Disease Clinical Research Center, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China.
Zaicheng XuDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Disease Clinical Research Center, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China.
Cong LanDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Disease Clinical Research Center, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China.
Yongchun ZengDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Disease Clinical Research Center, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China.
Zhi ChenDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Disease Clinical Research Center, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China.
Pedro A JoseDivision of Renal Disease & Hypertension, The George Washington University School of Medicine and Health Sciences, Washington, DC.
Ye ZhangDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Disease Clinical Research Center, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China. Electronic address: whiteyezi@163.com.
Chunyu ZengDepartment of Cardiology, Chongqing Institute of Cardiology, Chongqing Cardiovascular Disease Clinical Research Center, Daping Hospital, The Third Military Medical University, Chongqing, P.R. China. Electronic address: chunyuzeng01@163.com.
Army Medical University · CNDaping Hospital · CNGeorge Washington University · US

Funding

Spatiotemporal transregulation of D1-like angiotensin receptors in genetically...P01HL074940 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI CAREY, ROBERT MUNSON · 2004 to 2020
$31.8M
Renal Dopamine Receptor & RegulationR37HL023081 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI JOSE, PEDRO A. · 2007 to 2016
$4.3M
RENAL DOPAMINE RECEPTOR REGULATION AND FUNCTIONR01HL023081 · NHLBI · GEORGETOWN UNIVERSITY · PI JOSE, PEDRO A. · 1985 to 2006
$2.4M
NHLBI NIH HHS P01 HL074940NHLBI NIH HHS R01 HL023081NHLBI NIH HHS R37 HL023081
6 · The paper itself

Abstract

Both renin-angiotensin systems and insulin participate in kidney-involved blood pressure regulation. Activation of angiotensin II type 2 receptor (AT

Indexed as

AnimalsBlood PressureCell LineGene Expression RegulationHypertensionKidney Tubules, ProximalPhosphatidylinositol 3-KinasePhosphoinositide-3 Kinase InhibitorsProtein Kinase CProtein Kinase InhibitorsRatsRats, Inbred SHRRats, Inbred WKYReceptor, Angiotensin, Type 2Receptor, InsulinRenal EliminationAgtr2 protein, ratInsr protein, ratPhosphatidylinositol 3-KinasePhosphoinositide-3 Kinase InhibitorsProtein Kinase CProtein Kinase InhibitorsReceptor, Angiotensin, Type 2Receptor, InsulinSodiumSodium-Potassium-Exchanging ATPaseAngiotensin II type 2 receptorhypertensioninsulin receptorkidneyrenal proximal tubule cells

Identifiers

PMID29289466
PMCPMC6389274
OpenAlexW2771396825

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.