ArticleSurgery today2018
Laparoscopic surgery for locally advanced T4 colon cancer: the long-term outcomes and prognostic factors.
Article in Surgery today, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Risk of peritoneal metastasis following minimally invasive colectomy for locally advanced colon cancer: a systematic review and meta-analysis.The oncologist · 2025Pooled it
- A systematic review of the literature assessing operative blood loss and postoperative outcomes after colorectal surgery.International journal of colorectal disease · 2022Pooled it
- Surgical treatment of locally advanced right colon cancer invading neighboring organs.Frontiers in medicine · 2022Pooled it
- Laparoscopic surgery should be a viable option for T4 colon cancer: evidence from a propensity score matching analysis.Updates in surgery · 2026Observational
- Impact and evolution of minimal invasive surgery in a centralized colorectal service: trends, safety and oncological outcomes across 15 years.World journal of surgical oncology · 2025Article
- Article
- Prospective observational non-randomized trial protocol for surgical planner 3D image processing & reconstruction for locally advanced colon cancer.BMC surgery · 2024Article
- Does Adjuvant Chemotherapy Benefit Patients with T4 N0 Colon Cancer?Medicina (Kaunas, Lithuania) · 2024Article
- An artificial intelligence-designed predictive calculator of conversion from minimally invasive to open colectomy in colon cancer.Updates in surgery · 2024Article
- The long-term outcomes and prognostic factors about locally advanced right colon cancer: a retrospective cohort study.Journal of gastrointestinal oncology · 2024Article
- Recurrence After Colectomy for Locally Advanced Colon Cancer: Experience from a Developing Country.Indian journal of surgical oncology · 2023Article
- Change point analysis validation of the learning curve in laparoscopic colorectal surgery: Experience from a non-structured training setting.World journal of gastrointestinal endoscopy · 2022Article
- Post-operative outcomes in patients with locally advanced colon cancer: a comparison of operative approach.Surgical endoscopy · 2022Article
- Laparoscopic vs. open colectomy for T4 colon cancer: A meta-analysis and trial sequential analysis of prospective observational studies.Frontiers in surgery · 2022Review
- Minimally invasive surgeryWorld journal of clinical cases · 2021Article
- Tumor size improves the accuracy of the prognostic prediction of T4a stage colon cancer.Scientific reports · 2021Article
- Oncological outcomes following laparoscopic surgery for pathological T4 colon cancer: a propensity score-matched analysis.Surgery today · 2021Article
- Applicability of minimally invasive surgery for clinically T4 colorectal cancer.Scientific reports · 2020Article
- Favorable short-term oncologic outcomes following laparoscopic surgery for small T4 colon cancer: a multicenter comparative study.World journal of surgical oncology · 2020Article
- Feasibility and Safety of Laparoscopic Radical Colectomy for T4b Colon Cancer at a University Hospital in Vietnam.BioMed research international · 2020Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFor locally advanced pathological T4 (pT4) colon cancer, the safety and feasibility of laparoscopic procedures remain controversial. Therefore, this study aimed to assess short-term and long-term outcomes and to identify the prognostic factors in laparoscopic surgery for pT4 colon cancer.
methodsThe study group included 130 patients who underwent laparoscopic radical resection for pT4 colon and rectosigmoid cancer from January 2004 through December 2012. The short-term outcomes, long-term outcomes, and prognostic factors in pT4 colon cancer were analyzed.
resultsThe median operative time was 205 min, with a median blood loss of 10 ml. The conversion rate was 3.8%, and 13 patients (10.0%) had postoperative complications. The radial resection margin was positive in 1 patient (0.8%). The median follow-up time was 73 months. The 5-year overall survival (OS) and recurrence-free survival (RFS) were 77.2 and 63.5%, respectively. On a multivariate analysis, a male sex [hazard ratio (HR) 3.09, p < 0.001], lymph node ratio ≥ 0.06 (HR 2.35, p = 0.021), tumor diameter < 38 mm (HR 2.57, p = 0.007), and right-sided colon cancer (HR 2.11, p = 0.047) were significantly related to a poor OS.
conclusionsThese results suggest that laparoscopic surgery for pT4 colon cancer is safe and feasible, and the oncological outcomes are acceptable. Based on the present findings, select patients with locally advanced colon cancer should not be excluded from laparoscopic surgery.
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