Evidence map›Paper›PMID 29288276›Full record

ArticleSurgical endoscopy2018

HIFU, a noninvasive and effective treatment for chyluria: 15 years of experience.

Juhua Xiao, Ting Sun, Shouhua Zhang, Ming Ma, Xiaorong Yang, Jinshui Zhou, Jianfang Zhu, Fang Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Juhua XiaoDepartment of HIFU Treatment Room, The First Affiliated Hospital of Nanchang University, No. 17, Yongwai Road, Nanchang, 330006, China.
Ting SunDepartment of Urology Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Shouhua ZhangDepartment of General Surgery, Jiangxi Children's Hospital, Nanchang, 330006, China.
Ming MaDepartment of Urology Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Xiaorong YangDepartment of Urology Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Jinshui ZhouDepartment of HIFU Treatment Room, The First Affiliated Hospital of Nanchang University, No. 17, Yongwai Road, Nanchang, 330006, China.
Jianfang ZhuDepartment of HIFU Treatment Room, The First Affiliated Hospital of Nanchang University, No. 17, Yongwai Road, Nanchang, 330006, China.
Fang WangDepartment of HIFU Treatment Room, The First Affiliated Hospital of Nanchang University, No. 17, Yongwai Road, Nanchang, 330006, China. wfwajwu@126.com.
First Affiliated Hospital of Nanchang University · CNNanchang University · CNJiangxi Maternal and Child Health Hospital · CNJiangxi Provincial Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe current treatment therapies for chyluria are often invasive and recurrent. Here, we investigated a novel noninvasive treatment of chyluria with high-intensity focused ultrasound (HIFU) and evaluated its clinical efficacy.

methods155 patients with chyluria were treated with HIFU ablation and followed up over a period of 15 years from May 2000 to December 2015. Routine examinations including urine color observation, color Doppler ultrasound examination, blood serum test of Cr, BUN, and albumin, and detection of urinary chyle were performed before and after the treatment, 1 week, 1 and 6 months post-treatment, and followed up via telephone and other forms. We lost contact with 54 patients during the course of the study.

resultsIn the 101 complete cases, the serum levels of Cr and BUN and the color Doppler ultrasound examination did not reveal significant differences before and after the treatment. However, there was a significant increase in the hemoglobin and albumin levels, as well as the body weight after the HIFU treatment. The other 54 patients also showed an improvement of the symptoms after the HIFU treatment before losing contact.

conclusionsOur results suggest that the HIFU ablation therapy is a feasible, effective, and noninvasive method for the treatment of chyluria.

Indexed as

ForecastingAdultAgedAged, 80 and overChyleFemaleFollow-Up StudiesHigh-Intensity Focused Ultrasound AblationHumansMaleMiddle AgedTreatment OutcomeUrinary BladderUrinary Bladder DiseasesAblation therapyChyluriaHigh-intensity focused ultrasound (HIFU)Milky white urineNoninvasive treatment

Identifiers

PMID29288276
OpenAlexW2778235971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.