Evidence map›Paper›PMID 29288257›Full record

ArticleJournal of exposure science & environmental epidemiology2018

Predictors of blood volatile organic compound levels in Gulf coast residents.

Emily J Werder, Kaitlyn B Gam, Lawrence S Engel, Richard K Kwok, Christine C Ekenga, Matthew D Curry, David M Chambers, Aaron Blair, Aubrey K Miller, Linda S Birnbaum and 1 more

Abstract read
In one paragraph

Article in Journal of exposure science & environmental epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Blood BTEXS and heavy metal levels are associated with liver injury and systemic inflammation in Gulf states residents.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2020
    Article
  7. Determinants of environmental styrene exposure in Gulf coast residents.Journal of exposure science & environmental epidemiology · 2019
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Emily J WerderEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Kaitlyn B GamEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Lawrence S EngelEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Richard K KwokEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Christine C EkengaBrown School, Washington University in St. Louis, St. Louis, MO, USA.
Matthew D CurrySocial and Scientific Systems, Inc, Durham, NC, USA.
David M ChambersEmergency Response and Air Toxicants Branch, Division of Laboratory Sciences, National Center for Environmental Health, Atlanta, Georgia.
Aaron BlairOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Aubrey K MillerOffice of the Director, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Linda S BirnbaumOffice of the Director, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Dale P SandlerEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA. sandler@niehs.nih.gov.

Funding

Gulf Longitudinal Follow-up (GuLF) Worker StudyZIAES102945 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SANDLER, DALE P · 2010 to 2025
$15.3M
Studies of the fate of environmental contaminants in humans and animalsZIABC011476 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BIRNBAUM, LINDA · 2013 to 2019
$5.8M
Intramural NIH HHS Z99 ES999999NIEHS NIH HHS ZIA ES102945
6 · The paper itself

Abstract

To address concerns among Gulf Coast residents about ongoing exposures to volatile organic compounds, including benzene, toluene, ethylbenzene, o-xylene, and m-xylene/p-xylene (BTEX), we characterized current blood levels and identified predictors of BTEX among Gulf state residents. We collected questionnaire data on recent exposures and measured blood BTEX levels in a convenience sample of 718 Gulf residents. Because BTEX is rapidly cleared from the body, blood levels represent recent exposures in the past 24 h. We compared participants' levels of blood BTEX to a nationally representative sample. Among nonsmokers we assessed predictors of blood BTEX levels using linear regression, and predicted the risk of elevated BTEX levels using modified Poisson regression. Blood BTEX levels in Gulf residents were similar to national levels. Among nonsmokers, sex and reporting recent smoky/chemical odors predicted blood BTEX. The change in log benzene was -0.26 (95% CI: -0.47, -0.04) and 0.72 (0.02, 1.42) for women and those who reported odors, respectively. Season, time spent away from home, and self-reported residential proximity to Superfund sites (within a half mile) were statistically associated with benzene only, however mean concentration was nearly an order of magnitude below that of cigarette smokers. Among these Gulf residents, smoking was the primary contributor to blood BTEX levels, but other factors were also relevant.

Indexed as

AdultBenzeneEnvironmental MonitoringFemaleHumansHydrocarbons, AromaticLinear ModelsMaleMiddle AgedProspective StudiesSeasonsSmokingSoutheastern United StatesSurveys and QuestionnairesTolueneVolatile Organic CompoundsBenzeneHydrocarbons, AromaticTolueneVolatile Organic CompoundsBiomonitoringPersonal exposureVolatile organic compounds

Identifiers

PMID29288257
PMCPMC6013310

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.