Evidence map›Paper›PMID 29288231›Full record

ArticlePlant physiology2018

Sulforaphane Modifies Histone H3, Unpacks Chromatin, and Primes Defense.

Britta Schillheim, Irina Jansen, Stephani Baum, Alexander Beesley, Carsten Bolm, Uwe Conrath

Open access · hybridAbstract read
In one paragraph

Article in Plant physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
9.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 51 citations in OpenAlex.

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  17. Mitochondria-Microbiota Interaction in Neurodegeneration.Frontiers in aging neuroscience · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Britta SchillheimDepartment of Biology, RWTH Aachen University, Aachen 52056, Germany.ORCID 0000-0002-7477-9569
Irina JansenDepartment of Biology, RWTH Aachen University, Aachen 52056, Germany.
Stephani BaumDepartment of Biology, RWTH Aachen University, Aachen 52056, Germany.
Alexander BeesleyDepartment of Biology, RWTH Aachen University, Aachen 52056, Germany.
Carsten BolmDepartment of Chemistry, RWTH Aachen University, Aachen 52056, Germany.
Uwe ConrathDepartment of Biology, RWTH Aachen University, Aachen 52056, Germany uwe.conrath@bio3.rwth-aachen.de.ORCID 0000-0002-8503-1943
RWTH Aachen University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern crop production calls for agrochemicals that prime plants for enhanced defense. Reliable test systems for spotting priming-inducing chemistry, however, are rare. We developed an assay for the high-throughput search for compounds that prime microbial pattern-induced secretion of antimicrobial furanocoumarins (phytoalexins) in cultured parsley cells. The screen produced 1-isothiocyanato-4-methylsulfinylbutane (sulforaphane; SFN), a secondary metabolite in many crucifers, as a novel defense priming compound. While elucidating SFN's mode of action in defense priming, we found that in Arabidopsis (

Indexed as

ArabidopsisArabidopsis ProteinsChromatinGene Expression Regulation, PlantHigh-Throughput Screening AssaysHistonesHost-Pathogen InteractionsIsothiocyanatesLysineOomycetesOxidation-ReductionPetroselinumPhytoalexinsPromoter Regions, GeneticSesquiterpenesSulfoxidesArabidopsis ProteinsChromatinHistonesIsothiocyanatesLysinePhytoalexinsSesquiterpenessulforaphaneSulfoxidesSulfurTranscription FactorsWRKY6 protein, Arabidopsis

Identifiers

PMID29288231
PMCPMC5841731
OpenAlexW2777069404

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.