Evidence map›Paper›PMID 29288165›Full record

ReviewEMBO molecular medicine2018

Regenerating human epithelia with cultured stem cells: feeder cells, organoids and beyond.

Robert E Hynds, Paola Bonfanti, Sam M Janes

Open access · goldAbstract readReview
In one paragraph

Review in EMBO molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 78 citations in OpenAlex.

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  16. Innovative three-dimensional models for understanding mechanisms underlying lung diseases: powerful tools for translational research.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Robert E HyndsLungs for Living Research Centre, UCL Respiratory, University College London, London, UK.ORCID 0000-0002-2170-8791
Paola BonfantiThe Francis Crick Institute, London, UK p.bonfanti@ucl.ac.uk s.janes@ucl.ac.uk.ORCID 0000-0001-9655-3766
Sam M JanesLungs for Living Research Centre, UCL Respiratory, University College London, London, UK p.bonfanti@ucl.ac.uk s.janes@ucl.ac.uk.ORCID 0000-0002-6634-5939
Great Ormond Street Hospital · GBThe Francis Crick Institute · GBUniversity College London · GB

Funding

Cancer Research UK 17786Cancer Research UK 19310Cancer Research UK 20466Cancer Research UK 25253Medical Research Council G108/596Wellcome Trust 209199/Z/17/ZWellcome Trust WT107963/Z/15/ZWellcome Trust WT209199/Z/17/Z
6 · The paper itself

Abstract

More than 40 years ago, Howard Green's laboratory developed a method for long-term expansion of primary human epidermal keratinocytes by co-culture with 3T3 mouse embryonic fibroblasts. This was a breakthrough for

Indexed as

3T3 CellsAnimalsAutograftsCells, CulturedCoculture TechniquesEpithelial CellsFeeder CellsHumansMiceOrganoidsStem Cells3T3 cellsadult stem cellscell cultureepithelial cellsorganoids

Identifiers

PMID29288165
PMCPMC5801505
OpenAlexW2777408244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.