Evidence map›Paper›PMID 29288156›Full record

ArticleJournal of the American Heart Association2017

Left Ventricular Torsion Shear Angle Volume Approach for Noninvasive Evaluation of Diastolic Dysfunction in Preserved Ejection Fraction.

Oleg F Sharifov, Chun G Schiros, Inmaculada Aban, Gilbert J Perry, Louis J Dell'italia, Steven G Lloyd, Thomas S Denney, Himanshu Gupta

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Oleg F SharifovDepartment of Medicine, University of Alabama at Birmingham, AL.
Chun G SchirosDepartment of Medicine, University of Alabama at Birmingham, AL.
Inmaculada AbanDepartment of Biostatistics, University of Alabama at Birmingham, AL.
Gilbert J PerryDepartment of Medicine, University of Alabama at Birmingham, AL.
Louis J Dell'italiaDepartment of Medicine, University of Alabama at Birmingham, AL.
Steven G LloydDepartment of Medicine, University of Alabama at Birmingham, AL.
Thomas S DenneyDepartment of Electrical and Computer Engineering, Auburn University, Auburn, AL.
Himanshu GuptaDepartment of Medicine, University of Alabama at Birmingham, AL hgupta@cvapc.com.
University of Alabama at Birmingham · USBirmingham VA Medical Center · USAuburn University · US

Funding

Left Ventricular Torsional Hysteresis: A Global Parameter for Diastolic FunctionR01HL104018 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GUPTA, HIMANSHU · 2010 to 2014
$1.8M
NHLBI NIH HHS R01 HL104018
6 · The paper itself

Abstract

backgroundAccurate noninvasive diagnostic tools for evaluating left ventricular (LV) diastolic dysfunction (LVDD) are limited in preserved LV ejection fraction. We previously proposed the relationship of normalized rate of change in LV torsion shear angle (φ') to corresponding rate of change in LV volume (V') during early diastole (represented as -dφ'/dV') as a measure of LV diastolic function. We prospectively evaluated diagnostic accuracy of -dφ'/dV' in respect to invasive LV parameters. METHODS AND

resultsParticipants (n=36, age 61±7 years) with LV ejection fraction ≥50% and no acute myocardial infarction undergoing coronary angiography for chest pain and/or dyspnea evaluation were studied. High-fidelity invasive LV pressure measurements and cardiac magnetic resonance imaging with tissue tagging were performed. τ, the time constant of LV diastolic relaxation, was 58±10 milliseconds (mean±SD), and LV end-diastolic pressure was 14.5±5.5 mm Hg. Cardiac magnetic resonance imaging-derived -dφ'/dV' was 5.6±3.7. The value of -dφ'/dV' correlated with both τ and LV end-diastolic pressure (

conclusionsThe -dφ'/dV' obtained from the LV torsion volume loop is a promising parameter for assessing global LVDD with preserved LV ejection fraction and requires further evaluation.

Indexed as

Stroke VolumeAgedCardiac CatheterizationCoronary AngiographyDiastoleFemaleHeart Failure, DiastolicHumansMagnetic Resonance ImagingMaleMiddle AgedSensitivity and SpecificitySeverity of Illness IndexStress, MechanicalTorsion, MechanicalVentricular Dysfunction, Leftcardiac magnetic resonance imagingdiagnostic methodleft ventricular diastolic dysfunctionleft ventricular torsion shear angletorsion

Identifiers

PMID29288156
PMCPMC5778962
OpenAlexW2777008404

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.