Evidence map›Paper›PMID 29287991›Full record

ArticleMicrobes and infection2018

T cell phenotypes in women with Chlamydia trachomatis infection and influence of treatment on phenotype distributions.

Brian M O Ogendi, Rakesh K Bakshi, Kanupriya Gupta, Richa Kapil, LaDraka T Brown, Stephen J Jordan, Steffanie Sabbaj, Christen G Press, Jeannette Y Lee, William M Geisler

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbes and infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. UnveilingiScience · 2025
    Article
  2. Medicine and pharmacy reports · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Brian M O OgendiDepartment of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.
Rakesh K BakshiDepartment of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.
Kanupriya GuptaDepartment of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.
Richa KapilDepartment of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.
LaDraka T BrownDepartment of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.
Stephen J JordanDepartment of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.
Steffanie SabbajDepartment of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.
Christen G PressDepartment of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.
Jeannette Y LeeDepartment of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
William M GeislerDepartment of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address: wgeisler@uabmc.edu.
University of Alabama at Birmingham · USUniversity of Arkansas for Medical Sciences · US

Funding

UAB Center for Clinical and Translational Science (CCTS) UL1UL1TR000165 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2012 to 2013
$9.6M
Mechanisms and Correlates of Immune Protection against Genital Chlamydia in HumansR01AI093692 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GEISLER, WILLIAM M · 2012 to 2023
$4.5M
Midcareer Mentoring Award for Patient-Oriented Research in Chlamydia trachomatis InfectionK24AI125685 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WILLIAM M GEISLER · 2016 to 2026
$1.3M
NIAID NIH HHS K24 AI125685NIAID NIH HHS R01 AI093692
6 · The paper itself

Abstract

T cell phenotypes involved in the immune response to Chlamydia trachomatis (CT) have not been fully elucidated in humans. We evaluated differences in T cell phenotypes between CT-infected women and CT-seronegative controls and investigated changes in T cell phenotype distributions after CT treatment and their association with reinfection. We found a higher expression of T cell activation markers (CD38

Indexed as

Adaptive ImmunityAdolescentAdultAnti-Bacterial AgentsChlamydia InfectionsChlamydia trachomatisFemaleFollow-Up StudiesGene Expression RegulationHumansLymphocyte ActivationMembrane GlycoproteinsPhenotypeReceptors, ChemokineT-LymphocytesT-Lymphocyte SubsetsAnti-Bacterial AgentsMembrane GlycoproteinsReceptors, ChemokineChemokine receptorsChlamydia trachomatisPhenotypesT cell

Identifiers

PMID29287991
PMCPMC5851839
OpenAlexW2779305760

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.