Evidence map›Paper›PMID 29287989›Full record

ReviewMicrobes and infection

Immune responses to congenital cytomegalovirus infection.

Ilija Brizić, Lea Hiršl, William J Britt, Astrid Krmpotić, Stipan Jonjić

Abstract readReview
In one paragraph

Review in Microbes and infection. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
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  8. Article
  9. Vitiligo: are microbes to blame?Bioscience of microbiota, food and health · 2025
    Review
  10. Article
  11. Article
  12. Observational
  13. Immune surveillance of cytomegalovirus in tissues.Cellular & molecular immunology · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ilija BrizićDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia; Center for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Lea HiršlDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia; Center for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
William J BrittDepartment of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Pediatrics Infectious Disease, University of Alabama at Birmingham, Birmingham, AL, USA.
Astrid KrmpotićDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Stipan JonjićDepartment of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia; Center for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia. Electronic address: stipan.jonjic@medri.uniri.hr.

Funding

Congenital CMV and CNS Infection Mechanisms of Protective ImmunityR01AI089956 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI William Jarvis Britt · 2011 to 2026
$7.7M
Inflammation and Hearing Loss Following Congenital CMV InfectionR01DC015980 · NIDCD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BRITT, WILLIAM JARVIS, HIROSE, KEIKO · 2017 to 2021
$3.1M
NIAID NIH HHS R01 AI089956NIDCD NIH HHS R01 DC015980
6 · The paper itself

Abstract

Human cytomegalovirus (HCMV) is the most common cause of viral infection acquired in utero. Even though the infection has been studied for several decades, immune determinants important for virus control and mechanisms of long-term sequelae caused by infection are still insufficiently characterized. Animal models of congenital HCMV infection provide unique opportunity to study various aspects of human disease. In this review, we summarize current knowledge on the role of immune system in congenital CMV infection, with emphasis on lessons learned from mouse model of congenital CMV infection.

Indexed as

Adaptive ImmunityAnimalsCentral Nervous SystemCytomegalovirusCytomegalovirus InfectionsDisease Models, AnimalHumansImmunity, InnateBrain pathologyCongenital CMV infectionCytomegalovirusImmune responseVaccines

Identifiers

PMID29287989
PMCPMC6019571

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.