Evidence map›Paper›PMID 29286866›Full record

ArticleNutritional neuroscience2019

Omega-3 fatty acid deficiency impairs frontostriatal recruitment following repeated amphetamine treatment in rats: A 7 Tesla

Robert K McNamara, Jennifer D Schurdak, Ruth H Asch, Diana M Lindquist

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutritional neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Robert K McNamaraa Department of Psychiatry and Behavioral Neuroscience , University of Cincinnati College of Medicine , Cincinnati , OH 45267 , USA.
Jennifer D Schurdaka Department of Psychiatry and Behavioral Neuroscience , University of Cincinnati College of Medicine , Cincinnati , OH 45267 , USA.ORCID http://orcid.org/0000-0002-6570-9083
Ruth H Ascha Department of Psychiatry and Behavioral Neuroscience , University of Cincinnati College of Medicine , Cincinnati , OH 45267 , USA.
Diana M Lindquistb Imaging Research Center, Department of Radiology , Cincinnati Children's Hospital Medical Center , Cincinnati , OH 45229 , USA.
University of Cincinnati Medical Center · USCincinnati Children's Hospital Medical Center · US

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI MEINZEN-DERR, JAREEN, STRAWN, JEFFREY ROBERT · 2015 to 2024
$37.5M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR026314 · NCRR · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2009 to 2011
$14.3M
Neuroimaging study of risk factors for adolescent bipolar disorderR01MH097818 · NIMH · UNIVERSITY OF CINCINNATI · PI DELBELLO, MELISSA P, MCNAMARA, ROBERT K. · 2015 to 2019
$3.2M
Risk and protective factors for SGA-induced metabolic syndrome in bipolar youthR01DK097599 · NIDDK · UNIVERSITY OF CINCINNATI · PI MCNAMARA, ROBERT K. · 2013 to 2017
$1.7M
Risk and resilience factors for frontolimbic connectivity deficitsR01MH107378 · NIMH · UNIVERSITY OF CINCINNATI · PI MCNAMARA, ROBERT K. · 2016 to 2019
$1.7M
NCATS NIH HHS UL1 TR001425NCRR NIH HHS UL1 RR026314NIDDK NIH HHS R01 DK097599NIMH NIH HHS R01 MH097818NIMH NIH HHS R01 MH107378
6 · The paper itself

Abstract

Although attention deficit hyperactivity disorder is associated with deficits in docosahexaenoic acid (DHA), an omega-3 fatty acid implicated in dopamine and glutamate synaptic plasticity, its role in neuroplastic brain changes that occur following repeated amphetamine (AMPH) treatment are not known. This study used pharmacological magnetic resonance imaging to investigate the impact of repeated AMPH exposure and alterations in brain DHA levels on AMPH-induced brain activation patterns. Male rats were fed a diet with no

Indexed as

AmphetamineAnimalsBasal ForebrainBrainCorpus StriatumDocosahexaenoic AcidsErythrocytesGyrus CinguliLocomotionMagnetic Resonance ImagingMaleMotor CortexProsencephalonRats, Long-EvansSubstantia NigraThalamusAmphetamineDocosahexaenoic AcidsAmphetamineDocosahexaenoic acid (DHA)Magnetic resonance imagingOmega-3 fatty acidsRatSensitization

Identifiers

PMID29286866
PMCPMC6251752
OpenAlexW2781404293

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.