Evidence map›Paper›PMID 29286570›Full record

Trial reportPediatric blood & cancer2018

Identifying patient- and family-centered outcomes relevant to inpatient versus at-home management of neutropenia in children with acute myeloid leukemia.

Julia E Szymczak, Kelly D Getz, Rachel Madding, Brian Fisher, Elizabeth Raetz, Nobuko Hijiya, Maria M Gramatges, Meret Henry, Amir Mian, Staci D Arnold and 3 more

Open access · bronzeAbstract readClinical TrialComparative StudyMulticenter Study
In one paragraph

Trial report in Pediatric blood & cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 1 country.

Julia E SzymczakDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.ORCID 0000-0002-3230-8670
Kelly D GetzDivision of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Rachel MaddingDivision of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Brian FisherCenter for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.
Elizabeth RaetzDepartment of Pediatrics and Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.
Nobuko HijiyaDepartment of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0002-0199-054X
Maria M GramatgesDepartment of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, Texas.ORCID 0000-0002-0947-104X
Meret HenryDivision of Hematology/Oncology, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan.ORCID 0000-0001-5612-3294
Amir MianDepartment of Pediatric Hematology-Oncology, College of Medicine, Arkansas Children's Hospital, University of Arkansas Medical Sciences, Little Rock, Arkansas.
Staci D ArnoldDepartment of Pediatrics, Emory University, Atlanta, Georgia.
Catherine AftandilianDivision of Pediatric Hematology/Oncology, Stanford University School of Medicine and Lucile Packard Children's Hospital, Palo Alto, California.
Anderson B CollierDivision of Hematology/Oncology, Department of Pediatrics, University of Mississippi Medical Center, Jackson, Mississippi.
Richard AplencCenter for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.
Children's Hospital of Philadelphia · USArkansas Children's Hospital · USBaylor College of Medicine · USEmory University · USLucile Packard Children's Hospital · USNorthwestern University · USUniversity of Mississippi Medical Center · USUniversity of Pennsylvania · USUniversity of Utah · USWayne State University · US

Funding

Tumor Biology and Microenvironment (Program 1)P30CA022453 · NCI · WAYNE STATE UNIVERSITY · PI Julie Lynn Boerner · 1985 to 2026
$68.4M
NCI NIH HHS P30 CA022453
6 · The paper itself

Abstract

Efficacy of therapeutic strategies relative to patient- and family-centered outcomes in pediatric oncology must be assessed. We sought to identify outcomes important to children with acute myeloid leukemia and their families related to inpatient versus at-home management of neutropenia. We conducted qualitative interviews with 32 children ≥8 years old and 54 parents. Analysis revealed the impact of neutropenia management strategy on siblings, parent anxiety, and child sleep quality as being outcomes of concern across respondents. These themes were used to inform the design of a questionnaire that is currently being used in a prospective, multiinstitutional comparative effectiveness trial.

Indexed as

AnxietyInpatientsLeukemia, Myeloid, AcuteNeutropeniaParent-Child RelationsSiblingsAdolescentAdultChildChild, PreschoolHumansInfantInfant, NewbornProspective Studiesacute myeloid leukemianeutropeniapatient-reported outcomesqualitative methodology

Identifiers

PMID29286570
PMCPMC6857179
OpenAlexW2777852109

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.