Evidence map›Paper›PMID 29286298›Full record

ArticleInternational journal of molecular sciences2017

Simple Purification of Nicotiana benthamiana-Produced Recombinant Colicins: High-Yield Recovery of Purified Proteins with Minimum Alkaloid Content Supports the Suitability of the Host for Manufacturing Food Additives.

Anett Stephan, Simone Hahn-Löbmann, Fred Rosche, Mirko Buchholz, Anatoli Giritch, Yuri Gleba

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
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  5. Product safety aspects of plant molecular farming.Frontiers in bioengineering and biotechnology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Anett StephanNomad Bioscience GmbH, Biozentrum Halle, D-06120 Halle (Saale), Germany. stephan@nomadbioscience.com.
Simone Hahn-LöbmannNomad Bioscience GmbH, Biozentrum Halle, D-06120 Halle (Saale), Germany. hahn@nomadbioscience.com.
Fred RoscheFraunhofer Institute for Cell Therapy and Immunology, Department for Drug Design and Target Validation, D-06120 Halle (Saale), Germany. fred.rosche@izi.fraunhofer.de.
Mirko BuchholzFraunhofer Institute for Cell Therapy and Immunology, Department for Drug Design and Target Validation, D-06120 Halle (Saale), Germany. mirko.buchholz@izi.fraunhofer.de.
Anatoli GiritchNomad Bioscience GmbH, Biozentrum Halle, D-06120 Halle (Saale), Germany. giritch@nomadbioscience.com.ORCID 0000-0003-4672-0583
Yuri GlebaNomad Bioscience GmbH, Biozentrum Halle, D-06120 Halle (Saale), Germany. gleba@nomadbioscience.com.
Nomad Bioscience (Germany) · DEFraunhofer Institute for Cell Therapy and Immunology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colicins are natural non-antibiotic bacterial proteins with a narrow spectrum but an extremely high antibacterial activity. These proteins are promising food additives for the control of major pathogenic Shiga toxin-producing

Indexed as

Amino Acid SequenceAnimalsAnti-Bacterial AgentsBacterial ProteinsCattleColicinsFood AdditivesMeatMicrobial Sensitivity TestsNicotianaNicotinePlants, Genetically ModifiedRecombinant ProteinsShiga-Toxigenic Escherichia coliAnti-Bacterial AgentsBacterial ProteinsColicinsFood AdditivesNicotineRecombinant Proteinsalkaloidscolicinfood additivesNicotiana benthamiananicotineplant-made recombinant proteins

Identifiers

PMID29286298
PMCPMC5796045
OpenAlexW2778819185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.