Evidence map›Paper›PMID 29286002›Full record

ArticleeLife2017

Cell-accurate optical mapping across the entire developing heart.

Michael Weber, Nico Scherf, Alexander M Meyer, Daniela Panáková, Peter Kohl, Jan Huisken

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Towards advanced regenerative therapeutics to tackle cardio-cerebrovascular diseases.American heart journal plus : cardiology research and practice · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Getting to the Heart of Left-Right Asymmetry: Contributions from the Zebrafish Model.Journal of cardiovascular development and disease · 2021
    Review
  15. Cardiac optogenetics: a decade of enlightenment.Nature reviews. Cardiology · 2021
    Review
  16. The zebrafishProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael WeberMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID 0000-0001-8007-9975
Nico ScherfMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Alexander M MeyerMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
Daniela PanákováMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.ORCID 0000-0002-8739-6225
Peter KohlInstitute for Experimental Cardiovascular Medicine, University Heart Centre Freiburg - Bad Krozingen, Faculty of Medicine, Albert-Ludwigs University, Freiburg, Germany.
Jan HuiskenMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID 0000-0001-7250-3756

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organogenesis depends on orchestrated interactions between individual cells and morphogenetically relevant cues at the tissue level. This is true for the heart, whose function critically relies on well-ordered communication between neighboring cells, which is established and fine-tuned during embryonic development. For an integrated understanding of the development of structure and function, we need to move from isolated snap-shot observations of either microscopic or macroscopic parameters to simultaneous and, ideally continuous, cell-to-organ scale imaging. We introduce cell-accurate three-dimensional Ca

Indexed as

AnimalsHeartImaging, Three-DimensionalIntravital MicroscopyOptical ImagingOrganogenesisZebrafishbiophysicsCardiac conductionCardiologydevelopmental biologyimage analysisLight sheet microscopyOptical mappingOrganogenesisstem cellsstructural biologyzebrafish

Identifiers

PMID29286002
PMCPMC5747520

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.