Evidence map›Paper›PMID 29285953›Full record

Observational studyRenal failure2018

Incidence, characteristics and prognosis of acute kidney injury in Cameroon: a prospective study at the Douala General Hospital.

Marie Patrice E Halle, Ndjifoum Moselle Chipekam, Gérard Beyiha, Hermine Fouda, Aminata Coulibaly, Romuald Hentchoya, Folefack Francois Kaze, Namme Henry Luma, Gloria Ashuntantang

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Renal failure, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Review
  13. Observational
  14. Article
  15. Article
  16. Predictors of Acute Kidney Injury and Mortality in Intensive Care Unit at a Teaching Tertiary Hospital_ID.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020
    Article
  17. Observational
  18. Article
  19. Challenges and Outcomes of Paediatric Dialysis in a Tertiary Referral Hospital, Northwest Nigeria.Nigerian medical journal : journal of the Nigeria Medical Association
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marie Patrice E Hallea Faculty of Medicine and Pharmaceutical Sciences , University of Douala , Douala , Cameroon.
Ndjifoum Moselle Chipekama Faculty of Medicine and Pharmaceutical Sciences , University of Douala , Douala , Cameroon.
Gérard Beyihaa Faculty of Medicine and Pharmaceutical Sciences , University of Douala , Douala , Cameroon.
Hermine Foudab Department of Internal Medicine , Douala General Hospital , Douala , Cameroon.
Aminata Coulibalyc Intensive Care Unit , Douala General Hospital , Douala , Cameroon.
Romuald Hentchoyac Intensive Care Unit , Douala General Hospital , Douala , Cameroon.
Folefack Francois Kazed Faculty of Medicine and Biomedical Sciences , University of Yaounde , Yaounde , Cameroon.
Namme Henry Lumab Department of Internal Medicine , Douala General Hospital , Douala , Cameroon.
Gloria Ashuntantangb Department of Internal Medicine , Douala General Hospital , Douala , Cameroon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThere are limited data on AKI in sub-Saharan Africa. We aim to determine the incidence, characteristics and prognosis of AKI in Cameroon. PATIENTS AND

methodsA prospective study including all consenting acute admissions in the internal medicine and the ICU of a tertiary referral hospital in Cameroon from January 2015 to June 2016. Serum creatinine assay was done on admission, days 2 and 7 to diagnose AKI. For patients with AKI, serum creatinine was done on discharge, days 30, 60 and 90. AKI was defined according to the modified KDIGO 2012 criteria as an increase or decrease in serum creatinine of 3 mg/l or greater, or an increase of 50% or more from the reference value obtained at admission or the known baseline value. AKI severity was graded using KDIGO2012 criteria. Outcome measures were renal recovery, mortality and causes of death. Renal recovery was complete if serum creatinine between the first 90 days was less than baseline or reference, partial if less than diagnosis but not baseline or reference, no-recovery if creatinine did not decrease or if the patient remained on dialysis.

resultsOf the 2402 patients included, 536 developed AKI giving a global incidence of 22.3% and annual incidence of 15 per 100 patients-years. Of the 536 patients with AKI, 43.3% were at stage 3, 54.7% were males, median age was 56 years. Pre-renal AKI (61.4%) and acute tubular necrosis (28.9%) were the most frequent forms. Main etiologies were sepsis (50.4%) and volume depletion (31.6%). Renal outcome was unknown in 34% of patients. Of the 354 patients with known renal function at 3 months, 84.2% recovered completely, 14.7% partially and 1.1% progressed to CKD. Global mortality rate was 36.9% mainly due to sepsis.

conclusionsAKI is frequent in our setting, mainly due to sepsis and hypovolemia. It carries a poor prognosis.

Indexed as

Acute Kidney InjuryAgedCameroonCreatinineFemaleHospitals, GeneralHumansIncidenceIntensive Care UnitsKidney Function TestsMaleMiddle AgedPrognosisProspective StudiesRenal DialysisRetrospective StudiesCreatinineAcute kidney injuryCameroonDoualaincidenceprognosis

Identifiers

PMID29285953
PMCPMC6014289

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.