Evidence map›Paper›PMID 29285926›Full record

ArticleOrganic letters2018

Synthesis of Oligosaccharide Components of the Outer Core Domain of P. aeruginosa Lipopolysaccharide Using a Multifunctional Hydroquinone-Derived Reducing-End Capping Group.

Abhishek Vartak, Fatma M Hefny, Steven J Sucheck

Open access · greenAbstract read
In one paragraph

Article in Organic letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Abhishek VartakDepartment of Chemistry and Biochemistry, University of Toledo , 2801 West Bancroft Street, Toledo, Ohio 43606, United States.
Fatma M HefnyDepartment of Chemistry and Biochemistry, University of Toledo , 2801 West Bancroft Street, Toledo, Ohio 43606, United States.
Steven J SucheckDepartment of Chemistry and Biochemistry, University of Toledo , 2801 West Bancroft Street, Toledo, Ohio 43606, United States.ORCID 0000-0003-0082-3827
University of Toledo · US

Funding

Synthesis of Glycopeptide-Based Cancer Antigen VaccinesR15GM094734 · NIGMS · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI WALL, KATHERINE A · 2011 to 2015
$755k
NIGMS NIH HHS R15 GM094734
6 · The paper itself

Abstract

The synthesis of a trisaccharide (common to glycoform I and II) and a tetrasaccharide (common to glycoform I) from the outer core domain of Pseudomonas aeruginosa lipopolysaccharide (LPS) using a novel hydroquinone-based reducing-end capping group is reported. This multifunctional capping group was utilized as purification handle and was stable toward many common transformations in oligosaccharide synthesis. The access to outer-core LPS antigens with a TBDPS-protected hydroquinone (TPH) at the reducing end will be useful for glycan array and therapeutic glycoconjugate synthesis.

Indexed as

Pseudomonas aeruginosaCarbohydrate SequenceHydroquinonesLipopolysaccharidesMolecular StructureOligosaccharidesHydroquinonesLipopolysaccharidesOligosaccharides

Identifiers

PMID29285926
PMCPMC6169316
OpenAlexW2776686566

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.