ArticleMagnetic resonance in medicine2018
Simultaneous editing of GABA and glutathione at 7T using semi-LASER localization.
Article in Magnetic resonance in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Meta-analysis and open-source database for in vivo brain Magnetic Resonance spectroscopy in health and disease.Analytical biochemistry · 2023Pooled it
- Simultaneous edited MRS of GABA, glutathione, and ethanol.NMR in biomedicine · 2020Trial
- In vivo GABA detection by single-pulse editing with one shot.Magnetic resonance in medicine · 2025Article
- Proton Magnetic Resonance Spectroscopy for Pediatric Neuroimaging: Key Concepts for Practice.Seminars in ultrasound, CT, and MR · 2025Review
- GABA and glutamate measurements in temporal cortex of autistic children.Autism research : official journal of the International Society for Autism Research · 2024Article
- Glutamate measurements using edited MRS.Magnetic resonance in medicine · 2024Article
- Meta-analysis and Open-source Database for In Vivo Brain Magnetic Resonance Spectroscopy in Health and Disease.bioRxiv : the preprint server for biology · 2023Article
- Development of frontal GABA and glutamate supports excitation/inhibition balance from adolescence into adulthood.Progress in neurobiology · 2022Article
- Human brain functional MRS reveals interplay of metabolites implicated in neurotransmission and neuroenergetics.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Article
- Spectral editing inNMR in biomedicine · 2021Article
- GSH and GABA decreases in IDH1-mutated low-grade gliomas detected by HERMES spectral editing at 3 T in vivo.Neurochemistry international · 2020Article
- Effect of Age on GABA+ and Glutathione in a Pediatric Sample.AJNR. American journal of neuroradiology · 2020Article
- Article
- Advanced Hadamard-encoded editing of seven low-concentration brain metabolites: Principles of HERCULES.NeuroImage · 2019Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo demonstrate simultaneous editing of the two most commonly edited and overlapping signals, γ-aminobutyric acid (GABA), and glutathione (GSH), with Hadamard encoding and reconstruction of MEGA-edited spectroscopy (HERMES) using sLASER localization at 7T.
methodsDensity matrix simulations of HERMES at 7T were carried out and compared with phantom experiments. Additional phantom experiments were performed to characterize the echo time (TE) -dependent modulation of GABA- and GSH-edited HERMES spectra at TE of 80-160 ms. In vivo experiments were performed in 10 healthy volunteers, comparing HERMES (11 min) to sequentially acquired MEGA-sLASER detection of GABA and GSH (2 × 11 min).
resultsSimulations of HERMES show GABA- and GSH-edited spectra with negligible levels of crosstalk, and give modest agreement with phantom spectra. The TE series of GABA- and GSH-edited HERMES spectra modulate as a result of T
conclusionSimulated, phantom and in vivo measurements of HERMES show excellent segregation of GABA- and GSH-edited signals, and excellent agreement with separately acquired MEGA-sLASER data. HERMES allows two-fold acceleration of editing while maintaining spectral quality compared with sequentially acquired MEGA-sLASER measurements. Magn Reson Med 80:474-479, 2018. © 2017 International Society for Magnetic Resonance in Medicine.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.