Evidence map›Paper›PMID 29285686›Full record

ArticleRadiological physics and technology2018

Novel real-time tumor-contouring method using deep learning to prevent mistracking in X-ray fluoroscopy.

Toshiyuki Terunuma, Aoi Tokui, Takeji Sakae

Open access · hybridAbstract read
In one paragraph

Article in Radiological physics and technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

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  13. Enabling machine learning in X-ray-based procedures via realistic simulation of image formation.International journal of computer assisted radiology and surgery · 2019
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Toshiyuki TerunumaFaculty of Medicine, University of Tsukuba, Ten-nohdai 1-1-1, Tsukuba, 305-8575, Japan. terunuma@pmrc.tsukuba.ac.jp.ORCID http://orcid.org/0000-0002-5506-0743
Aoi TokuiGraduate School of Comprehensive Human Science, University of Tsukuba, Ten-nohdai 1-1-1, Tsukuba, 305-8575, Japan.
Takeji SakaeFaculty of Medicine, University of Tsukuba, Ten-nohdai 1-1-1, Tsukuba, 305-8575, Japan.
University of Tsukuba · JP

Funding

Japan Society for the Promotion of Science KAKENHI 17K09054Japan Society for the Promotion of Science KAKENHI 21611002Japan Society for the Promotion of Science KAKENHI 25461903
6 · The paper itself

Abstract

Robustness to obstacles is the most important factor necessary to achieve accurate tumor tracking without fiducial markers. Some high-density structures, such as bone, are enhanced on X-ray fluoroscopic images, which cause tumor mistracking. Tumor tracking should be performed by controlling "importance recognition": the understanding that soft-tissue is an important tracking feature and bone structure is unimportant. We propose a new real-time tumor-contouring method that uses deep learning with importance recognition control. The novelty of the proposed method is the combination of the devised random overlay method and supervised deep learning to induce the recognition of structures in tumor contouring as important or unimportant. This method can be used for tumor contouring because it uses deep learning to perform image segmentation. Our results from a simulated fluoroscopy model showed accurate tracking of a low-visibility tumor with an error of approximately 1 mm, even if enhanced bone structure acted as an obstacle. A high similarity of approximately 0.95 on the Jaccard index was observed between the segmented and ground truth tumor regions. A short processing time of 25 ms was achieved. The results of this simulated fluoroscopy model support the feasibility of robust real-time tumor contouring with fluoroscopy. Further studies using clinical fluoroscopy are highly anticipated.

Indexed as

AlgorithmsMachine LearningPattern Recognition, AutomatedFiducial MarkersFluoroscopyHumansLung NeoplasmsRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray ComputedX-RaysData augmentationImage recognitionMarkerless tumor trackingSupervised deep learningTumor contouringX-ray fluoroscopy

Identifiers

PMID29285686
PMCPMC5840203
OpenAlexW2781121728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.