ArticleThe journal of headache and pain2017
Characteristics and diagnoses of acute headache in pregnant women - a retrospective cross-sectional study.
Article in The journal of headache and pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Latest clinical recommendations on valproate use for migraine prophylaxis in women of childbearing age: overview from European Medicines Agency and European Headache Federation.The journal of headache and pain · 2018Guideline
- Thunderclap headache as a first manifestation of acute disseminated encephalomyelitis: case report and literature review.BMC neurology · 2024Review
- [Migraine and pregnancy : Gender-specific aspects and current knowledge].Der Nervenarzt · 2024Review
- Calcitonin gene-related peptide antagonists in pregnancy: a disproportionality analysis in VigiBaseThe journal of headache and pain · 2024Article
- Neurologic Consultations and Headache during Pregnancy and in Puerperium: A Retrospective Chart Review.Journal of clinical medicine · 2023Article
- Secondary headaches in pregnancy and the puerperium.Frontiers in neurology · 2023Review
- Medulloblastoma Presenting as Severe Headache during Pregnancy: A Case Report and Review of the Literature.Medicina (Kaunas, Lithuania) · 2022Review
- Sinusitis as a cause of insidious headache in a pregnant woman: A case report.Obstetric medicine · 2021Article
- Neurology of Preeclampsia and Related Disorders: an Update in Neuro-obstetrics.Current pain and headache reports · 2021Review
- Article
- Secondary Headaches During Pregnancy: When to Worry.Current neurology and neuroscience reports · 2019Review
- The Hypertensive Headache: a Review.Current pain and headache reports · 2019Review
- Brain imaging in pregnant women with acute headache.Journal of neurology · 2018Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute headache is one of the most frequent neurological symptoms in pregnant women. The early diagnosis of underlying secondary conditions has a major influence on patient outcome, especially in emergency settings. However, at the time being no well-established guideline for diagnostic evaluation of acute headache during pregnancy exists. In this study, we aimed to characterize acute headache in pregnant women concerning demographic, clinical, and diagnostic features, and to determine predictors of secondary headache.
methodsWe analysed retrospectively the data of 151 pregnant women receiving neurological consultation due to acute headache at the Charité Berlin between 2010 and 2016. To assess risk factors for secondary headache in these patients we compared multiple anamnestic and clinical features of the primary and secondary headache group.
results57.6% of the patients were diagnosed with primary headache, most common migraine and tension type headache. Concerning secondary headaches, the most common aetiologies were infections (29.7%) and hypertensive disorders (22.0%). The primary and secondary headache group were similar in most anamnestic and clinical features. In multivariate logistic regression analysis, secondary headache history [OR 6.6; 95% CI 1.3-33.1], elevated blood pressure [OR 7.2; 95% CI 2.3-22.6], fever [OR 12.1; 95% CI 1.3-111.0] and abnormal neurological examination [OR 9.9; 95% CI 2.7-36.3] represented independent predictors for secondary headache. Regarding additional diagnostic procedures, abnormal thrombocytes, GOT, GPT and CRP, proteinuria, pathologic results of lumbar puncture and neuroimaging were associated with secondary headache.
conclusionsSecondary headache disorders are common during pregnancy, occurring in over one third of acute headache cases receiving neurological consultation. Most anamnestic and clinical features may not allow a clear distinction between primary and secondary headaches. Clinicians should pay attention to the presence of secondary headache history, elevated blood pressure, fever and abnormal findings in the neurological examination. Additional investigations, including laboratory tests and neuroimaging, are essential for the diagnostic process.
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