ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2018
Pressure-induced end-plate fracture in the porcine spine: Is the annulus fibrosus susceptible to damage?
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 19 citations in OpenAlex.
- Exploring the Causes of Intervertebral Disc Annulus Fibrosus Impairment.Cellular and molecular bioengineering · 2025Review
- Skeletal growth and development dictate the processes of vertebral fracture in the pediatric spine; a review emphasizing fracture biomechanics of the vertebral body during the period of skeletal immaturity.Frontiers in pediatrics · 2025Review
- Porcine Functional Spine Unit in orthopedic research, a systematic scoping review of the methodology.Journal of experimental orthopaedics · 2022Article
- Delamination of the Annulus Fibrosus of the Intervertebral Disc: Using a Bovine Tail Model to Examine Effect of Separation Rate.Frontiers in bioengineering and biotechnology · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine if the mechanical properties of the annulus fibrosus (AF) are altered following end-plate fracture. Vertebral fractures, particularly those in the growth plate, are relatively common among adolescents. What is unclear is whether or not these fractures are also associated with concomitant damage to the intervertebral disc (IVD), in particular the AF.
methodsThe current study employed a high-rate IVD pressurization model to create growth plate fractures in the porcine cervical spine. Posterior AF mechanical properties and laminate adhesion strength were quantified in fractured spines and compared to samples obtained from non-pressurized, un-fractured spines.
resultsAF laminate adhesion strength was 31% lower in the fractured spines compared to the un-fractured spines.
conclusionThis decrease in laminate adhesion strength suggests that growth plate fracture damage is not isolated to the vertebra and results in microdamage to the interlamellar matrix of the AF. This may increase in the risk of progressive delamination of the AF, which is associated with IVD herniation. These slides can be retrieved under Electronic Supplementary Material.
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