Evidence map›Paper›PMID 29285557›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2018

Transfusion practices at end of life for hematopoietic stem cell transplant patients.

Winnie S Wang, Joseph D Ma, Sandahl H Nelson, Carolyn Revta, Gary T Buckholz, Carolyn Mulroney, Eric J Roeland

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03814486 (Etude Descriptive Retrospective de la Transfusion Plaquettaire Chez Des Patients Atteints d'hémopathie Maligne en Phase Palliative et Suivis au CHU de Besançon), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03814486 completednot on this map

Etude Descriptive Retrospective de la Transfusion Plaquettaire Chez Des Patients Atteints d'hémopathie Maligne en Phase Palliative et Suivis au CHU de Besançon

TypeobservationalSponsorCentre Hospitalier Universitaire de BesanconRan2017 to 2018Enrolled119ConditionsPlatelet Transfusion, Palliative CareArmsdescriptive
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Transfusion as a Palliative Strategy.Current oncology reports · 2019
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Winnie S WangInternal Medicine, University of California (UC), San Diego, San Diego, CA, USA.
Joseph D MaSkaggs School of Pharmacy & Pharmaceutical Sciences, UC San Diego, La Jolla, CA, USA.
Sandahl H NelsonDepartment of Cancer Prevention and Control, UC San Diego Moores Cancer Center, La Jolla, CA, USA.
Carolyn RevtaDivision of Hematology/Oncology, Doris A. Howell Palliative Care Service, UC San Diego Moores Cancer Center, 3855 Health Sciences Drive, MC 0987, La Jolla, CA, 92093, USA.
Gary T BuckholzDivision of Hematology/Oncology, Doris A. Howell Palliative Care Service, UC San Diego Moores Cancer Center, 3855 Health Sciences Drive, MC 0987, La Jolla, CA, 92093, USA.
Carolyn MulroneyBlood and Marrow Transplant, UC San Diego Moores Cancer Center, La Jolla, CA, USA.
Eric J RoelandDivision of Hematology/Oncology, Doris A. Howell Palliative Care Service, UC San Diego Moores Cancer Center, 3855 Health Sciences Drive, MC 0987, La Jolla, CA, 92093, USA. eroeland@ucsd.edu.

Funding

UC San Diego Clinical and Translational Research InstituteKL2TR001444 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEPP, COLIN A. · 2015 to 2024
$15.4M
Cambia Health Foundation Sojourns Scholar AwardNCATS NIH HHS KL2 TR001444NCI NIH HHS L30 CA199550UC San Diego Clinical Translational Research Institute KL2 Career Development Award KL2TR001444
6 · The paper itself

Abstract

purposeLimited data exist regarding transfusion practices at end of life (EOL) for hematopoietic stem cell transplant (HSCT) patients. The purpose of this study was to examine red blood cell (RBC) and platelet transfusion practices in HSCT patients who enrolled or did not enroll in hospice.

methodsThis was a single-center, retrospective chart review in deceased HSCT patients. The primary objective was to determine the mean difference between the last transfusion and death in HSCT patients (n = 116) who enrolled or did not enroll in hospice.

resultsSixteen (14%) and 100 (86%) patients were enrolled in hospice and not enrolled in hospice, respectively. Hospice patients observed a larger mean difference between death and last transfusion (45.9 ± 66.7 vs. 14.6 ± 48.1 days, p < 0.0001). A higher amount of platelet, but not RBC, transfusions occurred in patients not enrolled in hospice (p = 0.04). The last transfusion that occurred more than 96 h before death was observed in 12 (75%) and 22 (22%) in hospice and non-hospice patients, respectively. For HSCT patients not enrolled in hospice, 17 patients received a transfusion on the same day of death and 31 patients received the last transfusion 24 h before death.

conclusionsBlood transfusion practices differed in HSCT patients enrolled and not enrolled in hospice. For most patients not enrolled in hospice, the last transfusion occurred 24 h before death. Future efforts should explore if limited access to blood products is a barrier to hospice enrollment for HSCT patients.

Indexed as

Hematopoietic Stem Cell TransplantationPlatelet TransfusionPractice Patterns, Physicians'Transplant RecipientsAdultAgedFemaleHematologic NeoplasmsHospice CareHumansMaleMiddle AgedRetrospective StudiesTerminal CareBlood transfusionEnd of lifeHematologic malignanciesHospiceStem cell transplantation

Identifiers

PMID29285557
PMCPMC5924436

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.