ArticleAdvanced biomedical research2017
Vitamin D Status in Small Vessel and Large Vessel Ischemic Stroke Patients: A Case-control Study.
Article in Advanced biomedical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 15 citations in OpenAlex.
- Vitamin D: The silent rescuer from ischemic stroke.Annals of medicine and surgery (2012) · 2022Article
- The combined presence of hypertension and vitamin D deficiency increased the probability of the occurrence of small vessel disease in China.BMC neurology · 2019Article
- Immune-inflammatory, oxidative stress and biochemical biomarkers predict short-term acute ischemic stroke death.Metabolic brain disease · 2019Article
- Vitamin D in Neurological Diseases: A Rationale for a Pathogenic Impact.International journal of molecular sciences · 2018Review
- The association between the serum level of vitamin D and ischemic heart disease: a study from Jordan.Vascular health and risk management · 2018Observational
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVitamin D insufficiency is a globally widespread issue. Recent studies have reported a high prevalence of Vitamin D deficiency in Middle-East countries. Studies have shown negative effects of Vitamin D deficiency on endothelium and related diseases such as ischemic brain stroke. Here, we assessed Vitamin D status in patients with different types of ischemic brain stroke and control group. MATERIALS AND
methodsSeventy-five patients (49.3% small vessel, 50.7% large vessel) and 75 controls, matched for age (68.01 ± 10.94 vs. 67.64 ± 10.24) and sex (42 male and 33 female) were recruited. 25(OH) D levels were measured by Chemiluminescence immunoassay. 25(OH) D status was considered as severely, moderately, or mildly deficient and normal with 25(OH) D levels of less than 5, 5-10, 10-16, and >16 ng/ml, respectively.
resultsMean ± standard error concentration of 25(OH) D in cases and controls were 17.7 ± 1.5 and 26.9 ± 1.6 (
conclusionVitamin D deficiency significantly increases the risk of ischemic stroke, favoring the types with the pathogenesis of large vessel strokes.
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