ArticleKidney research and clinical practice2017
Relationship between serum uric acid and mortality among hemodialysis patients: Retrospective analysis of Korean end-stage renal disease registry data.
Article in Kidney research and clinical practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Pooled it
- Hyperuricemia prevalence and its risk factors in uremic patients undergoing maintenance hemodialysis.BMC nephrology · 2025Article
- Nonlinearity association between hyperuricemia and all-cause mortality in patients with chronic kidney disease.Scientific reports · 2024Article
- Association between serum uric acid and all-cause and cardiovascular-related mortality in hemodialysis patients.Frontiers in nutrition · 2024Article
- Association between serum uric acid levels and clinical outcomes in patients with acute kidney injury.Renal failure · 2023Article
- Association between serum uric acid levels and long-term mortality of metabolic dysfunction-associated fatty liver disease: a nationwide cohort study.Diabetology & metabolic syndrome · 2023Article
- Nutritional and Hydration Status and Adherence to Dietary Recommendations in Dalmatian Dialysis Patients.Nutrients · 2022Article
- Urate-lowering therapy for patients with gout on hemodialysis.International journal of rheumatic diseases · 2022Article
- The Impact of an Elevated Uric Acid Level on the Prevalence of Coronary Artery Disease in Pancreas Transplant Candidates with Type 1 Diabetes: A Cross Sectional Study.Journal of clinical medicine · 2022Article
- Changes in plasma sclerostin level associated with use of a medium cut-off dialyzer in end-stage renal disease.Kidney research and clinical practice · 2021Article
- Uric acid and left ventricular hypertrophy: another relationship in hemodialysis patients.Clinical kidney journal · 2021Article
- Hyperuricemia, the heart, and the kidneys - to treat or not to treat?Renal failure · 2020Review
- Low serum uric acid levels increase the risk of all-cause death and cardiovascular death in hemodialysis patients.Renal failure · 2020Observational
- Extreme hyperuricemia is a risk factor for infection-related deaths in incident dialysis patients: a multicenter prospective cohort study.Renal failure · 2020Article
- Relationship between serum uric acid and all-cause mortality in dialysis patients: like being in wonderland, disoriented.Renal failure · 2020Article
- Association of hyperuricemia and serum uric acid lowering therapy with mortality in hemodialysis patients.Renal failure · 2020Article
- Association between Serum Uric Acid Levels, Nutritional and Antioxidant Status in Patients on Hemodialysis.Nutrients · 2020Article
- Serum Uric Acid and Mortality Risk Among Hemodialysis Patients.Kidney international reports · 2020Article
- Chronic kidney disease attenuates the impact of obesity on quality of life.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is thought that hyperuricemia might lower the risk of mortality among hemodialysis patients, unlike in the general population, but the evidence is controversial. The aim of the current study was to evaluate the impact of serum uric acid level on the long-term clinical outcomes of hemodialysis patients in Korea.
methodsRetrospective analysis was performed on data from the End-Stage Renal Disease Registry of the Korean Society of Nephrology. This included data for 7,333 patients (mean age, 61 ± 14 years; 61% male) who received hemodialysis from January 2001 through April 2015. Initial laboratory data were used in the analysis.
resultsThe mean serum uric acid level in this study was 7.1 ± 1.7 mg/dL. Body mass index, normalized protein catabolic rate, albumin, and cholesterol were positively correlated with serum uric acid level after controlling for age and sex. After controlling for demographic data, comorbidities, and residual renal function, a higher uric acid level was independently associated with a significantly lower all-cause mortality (hazard ratio [HR], 0.90 per 1 mg/dL increase in uric acid level; 95% confidence interval [CI], 0.83-0.97;
conclusionHyperuricemia was strongly associated with a lower risk of all-cause mortality, but there seems to be no significant association between serum uric acid level and cardiovascular mortality among Korean hemodialysis patients with end-stage renal disease.
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