Evidence map›Paper›PMID 29285357›Full record

ArticleMolecular and clinical oncology2017

Utility of chemoradioselection for the optimization of treatment intensity in advanced hypopharyngeal and laryngeal carcinoma.

Muneyuki Masuda, Takahiro Wakasaki, Satoshi Toh, Yoshinori Uchida, Hidefumi Rikimaru, Naonobu Kunitake, Yuichiro Higaki

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular and clinical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Muneyuki MasudaDepartment of Head and Neck Surgery, National Kyushu Cancer Center, Minamiku, Fukuoka 811-1395, Japan.
Takahiro WakasakiDepartment of Head and Neck Surgery, National Kyushu Cancer Center, Minamiku, Fukuoka 811-1395, Japan.
Satoshi TohDepartment of Head and Neck Surgery, National Kyushu Cancer Center, Minamiku, Fukuoka 811-1395, Japan.
Yoshinori UchidaDepartment of Head and Neck Surgery, National Kyushu Cancer Center, Minamiku, Fukuoka 811-1395, Japan.
Hidefumi RikimaruDepartment of Head and Neck Surgery, National Kyushu Cancer Center, Minamiku, Fukuoka 811-1395, Japan.
Naonobu KunitakeDepartment of Radiology, National Kyushu Cancer Center, Minamiku, Fukuoka 811-1395, Japan.
Yuichiro HigakiDepartment of Head and Neck Surgery, National Kyushu Cancer Center, Minamiku, Fukuoka 811-1395, Japan.
National Hospital Organization Kyushu Cancer Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Definitive concomitant chemoradiotherapy (CRT) with high-dose cis-platinum (CDDP) is a current standard protocol for advanced laryngeal and hypopharyngeal cancer sparing surgery for salvage. However, this modality is associated with limited feasibility and frequent sever toxicities. In the present study, a 'chemoradioselection' protocol with minimal toxicity was developed using initial response to CRT as a biomarker for patient selection. Between 2000, March and 2012, September 123 patients with stage III (44), IV (79) laryngeal (64) and hypopharyngeal carcinoma (59) excluding T4 cases were enrolled to this protocol. Two cycles of split (15 mg/m

Indexed as

chemoradioselectionlaryngo-esophageal dysfunction free survivaloptimization of therapeutic intensitysurvival benefit of surgerytoxicities

Identifiers

PMID29285357
PMCPMC5740821
OpenAlexW2765711447

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.