ArticleOncotarget2017
Depression and its impact on health-related quality of life among Chinese inpatients with lung cancer.
Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 30 citations in OpenAlex.
- Moderating Effect of Muscular Strength in the Association Between Cancer and Depressive Symptomatology.Healthcare (Basel, Switzerland) · 2025Article
- Epidemiological Analysis of Global and Regional Lung Cancer Mortality: Based on 30-Year Data Analysis of Global Burden Disease Database.Healthcare (Basel, Switzerland) · 2023Article
- Impact of postanesthesia care unit delirium on self-reported cognitive function and perceived health status: a prospective observational cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Observational
- Overlap of Depressive Symptoms with Health-Related Quality-of-Life Measures.PharmacoEconomics · 2021Article
- Quality of Life and Psychological Distress of Lung Cancer Patients Undergoing Chemotherapy.World journal of oncology · 2021Article
- Observational
- The relation between psychological profiles and quality of life in patients with lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Prevalence and risk factors of depression in patients with lung cancer: protocol for a systematic review and meta-analysis.BMJ open · 2019Article
- Prevalence and risk factors of anxiety and depression in Chinese patients with lung cancer：a cross-sectional study.Cancer management and research · 2019Article
- Factors contributing to cancer-related suicide: A study of root-cause analysis reports.Psycho-oncology · 2018Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Depression is of great concern for patients with cancer. A detailed epidemiological profile of depression in Chinese patients with lung cancer and whether depression impacts patients' health-related quality of life (HRQOL) remain unknown. This study examined the prevalence and socio-demographic and clinical correlates of depression and its effect on HRQOL in Chinese inpatients with lung cancer of two large general hospitals. A total of 148 inpatients were consecutively recruited, and administered with a standardized questionnaire to collect socio-demographic and clinical data. Depression and HRQOL were assessed with the Hospital Anxiety and Depression Scale and World Health Organization QOL Scale Brief Version, respectively. As high as 43.2% Chinese inpatients with lung cancer had clinically significant depressive symptoms. Multiple logistic regression found that depression was significantly associated with moderate-to-severe pain (OR: 4.43), metastatic cancer (OR: 3.63), a short duration after cancer diagnosis (OR: 1.04), poor performance status (OR: 3.41), and small-cell cancer (OR: 4.52). Depressed patients had significantly poorer HRQOL than not depressed patients in terms of all four domains of HRQOL. After controlling for the potential confounding effects of socio-demographic and clinical factors with analysis of covariance, these group-differences in physical (F = 29.074,
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