Evidence map›Paper›PMID 29285120›Full record

ArticleExperimental and therapeutic medicine2017

Protective efficacy of inhaled quercetin for radiation pneumonitis.

Meng Qin, Weijuan Chen, Juanjuan Cui, Wentao Li, Dongmei Liu, Weifen Zhang

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Meng QinDepartment of Pharmaceutics, College of Pharmacy, Weifang Medical University, Weifang, Shandong 261053, P.R. China.
Weijuan ChenDepartment of Pathology, People's Hospital of Shouguang, Weifang, Shandong 262700, P.R. China.
Juanjuan CuiDepartment of Pharmaceutics, College of Pharmacy, Weifang Medical University, Weifang, Shandong 261053, P.R. China.
Wentao LiLaboratory of Pharmacology, College of Clinical Medicine, Weifang Medical University, Weifang, Shandong 261053, P.R. China.
Dongmei LiuDepartment of Pharmaceutics, College of Pharmacy, Weifang Medical University, Weifang, Shandong 261053, P.R. China.
Weifen ZhangDepartment of Pharmaceutics, College of Pharmacy, Weifang Medical University, Weifang, Shandong 261053, P.R. China.
Weifang Medical University · CNWeifang People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiation pneumonitis is a clinical problem with a high incidence. Once the onset of radiation pneumonitis has occurred, the administration of antioxidants and anti-inflammatory agents is the most commonly used method of clinical treatment. Quercetin (Que) is a common flavonoid, with potent anti-inflammatory and anti-oxidant activities. In the present study, the therapeutic effect of inhaled Que on radiation-induced radiation pneumonitis in rats was investigated. Treatment with Que via inhalation was shown to increase the number of leukocytes and erythrocytes in the blood, and reduce the number of inflammatory cells in bronchoalveolar lavage fluid. Histological examination of lung tissue indicated that inhaled Que reduced hemorrhaging and the infiltration of inflammatory cells, and suppressed the expression of the proinflammatory cytokines transforming growth factor-β

Indexed as

inhalationpharmacodynamicsquercetinradiation pneumonitisrats

Identifiers

PMID29285120
PMCPMC5740811
OpenAlexW2760847321

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.