ArticleExperimental and therapeutic medicine2017
Birth weight and type 2 diabetes: A meta-analysis.
Article in Experimental and therapeutic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 53 citations in OpenAlex.
- Early-life exposures, biological age acceleration, and type 2 diabetes in adulthood: mediation analyses in the UK Biobank.GeroScience · 2026Article
- Birth weight and prematurity for predicting type 2 diabetes mellitus: a prognostic review.The Cochrane database of systematic reviews · 2025Article
- Prevalence and factors associated with hypertension among children attending pre-schools in Dar es Salaam, Tanzania.Italian journal of pediatrics · 2025Article
- Editorial: Neglected nuances in gestational diabetes.Frontiers in clinical diabetes and healthcare · 2025Article
- Genetic distance and ancestry proportion modify the association between maternal genetic risk score of type 2 diabetes and fetal growth.Human genomics · 2024Article
- Association of birth weight with type 2 diabetes mellitus and the mediating role of fatty acids traits: a two-step mendelian randomization study.Lipids in health and disease · 2024Article
- Long-term health risk of offspring born from assisted reproductive technologies.Journal of assisted reproduction and genetics · 2024Review
- Effects of in-utero personal exposure to PMScientific reports · 2023Article
- Effects of In-Utero Personal Exposure to PM2.5 Sources and Components on Birthweight.Research square · 2023Article
- Birth weight is associated with obesity and T2DM in adulthood among Chinese women.BMC endocrine disorders · 2022Article
- The Association of Self-Reported Birthweight with Lung Function and Respiratory Diseases: Results from a Multi-Centre, Multi-Case Control Study in Italy.International journal of environmental research and public health · 2022Article
- Association between indoor residual spraying and pregnancy outcomes: a quasi-experimental study from Uganda.International journal of epidemiology · 2022Article
- In-utero personal exposure to PMEnvironmental advances · 2022Article
- The impact of birthweight on subsequent phenotype of type 2 diabetes in later life.Diabetic medicine : a journal of the British Diabetic Association · 2022Article
- Effects of Δ9-Tetrahydrocannibinol (THC) on Obesity at Different Stages of Life: A Literature Review.International journal of environmental research and public health · 2022Review
- Association between maximum temperature and PMEnvironmental epidemiology (Philadelphia, Pa.) · 2021Article
- Manipulation of intestinal microbiome as potential treatment for insulin resistance and type 2 diabetes.European journal of nutrition · 2021Review
- Prevalence of depressive and anxiety symptoms in women with gestational diabetes: a longitudinal cohort study.Acta diabetologica · 2021Article
- Genome-wide association study identifying novel variant for fasting insulin and allelic heterogeneity in known glycemic loci in Chilean adolescents: The Santiago Longitudinal Study.Pediatric obesity · 2021Article
- Body Mass Index and Birth Weight Improve Polygenic Risk Score for Type 2 Diabetes.Journal of personalized medicine · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of T2DM is increasing around the world on a yearly basis. A meta-analysis was conducted to analyze the association between birth weight and incidence of type 2 diabetes mellitus (T2DM). A literature search was performed from January 1990 to June 2016 in PubMed, ScienceDirect, SpringerLink, China National Knowledge Infrastructure and Chinese Biomedical Literature Database. After reviewing characteristics of all the included studies systematically, a meta-analytical method was employed to calculate the pooled odds ratios (ORs) and associated 95% confidence intervals (CI) from random-effects models. Heterogeneity was assessed by Q-statistic test. Funnel plot, Begg's and Egger's linear regression tests were applied to evaluate publication bias. A sensitivity analysis was also performed to assess the robustness of results. According to inclusion and exclusion criteria, 8 studies were selected to be included in the meta-analysis. Compared with normal birth weight (2,500-4,000 g), low birth weight (<2,500 g) was associated with an increased risk of T2DM (OR, 1.55; 95% CI, 1.39-1.73; P<0.001). No significant difference was observed between high birth weight (>4,000 g) and normal birth weight in terms of the risk of T2DM (OR, 0.98; 95% CI, 0.79-1.22). Compared with high birth weight, low birth weight was associated with an increased risk of diabetes mellitus (OR, 1.58; 95% CI, 1.30-1.93; P<0.001). These findings indicated that there may be an inverse linear association between birth weight and T2DM.
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Registered trials
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