ArticleProceedings of the National Academy of Sciences of the United States of America2018
Interplay of structure, elasticity, and dynamics in actin-based nematic materials.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Gene-driven self-morphing microtubule-based active matter.Nature materials · 2026Article
- Coupling of colloidal rods to the dynamic order of active nematic films.Soft matter · 2026Article
- Topological control of spontaneous failure in active nematic solids.Nature materials · 2026Article
- Motor crosslinking augments elasticity in active nematics.Soft matter · 2024Article
- Measuring response functions of active materials from data.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Complex-tensor theory of simple smectics.Nature communications · 2023Article
- Spontaneous flow created by active topological defects.The European physical journal. E, Soft matter · 2022Review
- Filopodia rotate and coil by actively generating twist in their actin shaft.Nature communications · 2022Article
- Logic operations with active topological defects.Science advances · 2022Article
- Nano/Micromotors in Active Matter.Micromachines · 2022Review
- Extensile to contractile transition in active microtubule-actin composites generates layered asters with programmable lifetimes.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Submersed micropatterned structures control active nematic flow, topology, and concentration.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Structures and topological defects in pressure-driven lyotropic chromonic liquid crystals.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Properties of twisted topological defects in 2D nematic liquid crystals.Soft matter · 2021Article
- Transformation between elastic dipoles, quadrupoles, octupoles, and hexadecapoles driven by surfactant self-assembly in nematic emulsion.Science advances · 2021Article
- Article
- Activity pulses induce spontaneous flow reversals in viscoelastic environments.Journal of the Royal Society, Interface · 2021Article
- Machine learning active-nematic hydrodynamics.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Pattern formation and polarity sorting of driven actin filaments on lipid membranes.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Carbon nanotube-reduced graphene oxide fiber with high torsional strength from rheological hierarchy control.Nature communications · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Achieving control and tunability of lyotropic materials has been a long-standing goal of liquid crystal research. Here we show that the elasticity of a liquid crystal system consisting of a dense suspension of semiflexible biopolymers can be manipulated over a relatively wide range of elastic moduli. Specifically, thin films of actin filaments are assembled at an oil-water interface. At sufficiently high concentrations, one observes the formation of a nematic phase riddled with [Formula: see text] topological defects, characteristic of a two-dimensional nematic system. As the average filament length increases, the defect morphology transitions from a U shape into a V shape, indicating the relative increase of the material's bend over splay modulus. Furthermore, through the sparse addition of rigid microtubule filaments, one can gain additional control over the liquid crystal's elasticity. We show how the material's bend constant can be raised linearly as a function of microtubule filament density, and present a simple means to extract absolute values of the elastic moduli from purely optical observations. Finally, we demonstrate that it is possible to predict not only the static structure of the material, including its topological defects, but also the evolution of the system into dynamically arrested states. Despite the nonequilibrium nature of the system, our continuum model, which couples structure and hydrodynamics, is able to capture the annihilation and movement of defects over long time scales. Thus, we have experimentally realized a lyotropic liquid crystal system that can be truly engineered, with tunable mechanical properties, and a theoretical framework to capture its structure, mechanics, and dynamics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.