Evidence map›Paper›PMID 29284710›Full record

ReviewGenes & development2017

Chromatin and nucleosome dynamics in DNA damage and repair.

Michael H Hauer, Susan M Gasser

Open access · diamondAbstract readReview
In one paragraph

Review in Genes & development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 187 papers.

0numbers the graph read from it
0cells of the map it votes in
187citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

187 citing papers in PubMed, 330 citations in OpenAlex.

  1. Article
  2. Article
  3. Topology Resetting During Transcription-Coupled Nucleotide Excision Repair.International journal of molecular sciences · 2026
    Review
  4. Article
  5. Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Chromatin Control of EBV Infection and Latency.Current topics in microbiology and immunology · 2025
    Article
  17. Article
  18. Rewiring cancer: 3D genome determinants of cancer hallmarks.Current opinion in genetics & development · 2025
    Review
  19. Article
  20. Article

127 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael H HauerFriedrich Miescher Institute for Biomedical Research, CH-4058 Basel, Switzerland.
Susan M GasserFriedrich Miescher Institute for Biomedical Research, CH-4058 Basel, Switzerland.
Friedrich Miescher Institute · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromatin is organized into higher-order structures that form subcompartments in interphase nuclei. Different categories of specialized enzymes act on chromatin and regulate its compaction and biophysical characteristics in response to physiological conditions. We present an overview of the function of chromatin structure and its dynamic changes in response to genotoxic stress, focusing on both subnuclear organization and the physical mobility of DNA. We review the requirements and mechanisms that cause chromatin relocation, enhanced mobility, and chromatin unfolding as a consequence of genotoxic lesions. An intriguing link has been established recently between enhanced chromatin dynamics and histone loss.

Indexed as

DNA DamageDNA RepairChromatinHistonesNucleosomesChromatinHistonesNucleosomeschromatin structureDNA damagehistonesnuclear organizationnucleosome remodelers

Identifiers

PMID29284710
PMCPMC5769766
OpenAlexW2778217919

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.