Evidence map›Paper›PMID 29284662›Full record

ArticleThe Journal of general physiology2018

Junctional trafficking and restoration of retrograde signaling by the cytoplasmic RyR1 domain.

Alexander Polster, Stefano Perni, Dilyana Filipova, Ong Moua, Joshua D Ohrtman, Hicham Bichraoui, Kurt G Beam, Symeon Papadopoulos

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of general physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Alexander PolsterDepartment of Physiology and Biophysics, University of Colorado Denver Anschutz Medical Campus, Denver, CO.ORCID 0000-0003-2985-6518
Stefano PerniDepartment of Physiology and Biophysics, University of Colorado Denver Anschutz Medical Campus, Denver, CO.ORCID 0000-0002-0591-4376
Dilyana FilipovaInstitute of Vegetative Physiology, University Hospital of Cologne, Cologne, Germany.
Ong MouaDepartment of Physiology and Biophysics, University of Colorado Denver Anschutz Medical Campus, Denver, CO.
Joshua D OhrtmanDepartment of Physiology and Biophysics, University of Colorado Denver Anschutz Medical Campus, Denver, CO.
Hicham BichraouiDepartment of Physiology and Biophysics, University of Colorado Denver Anschutz Medical Campus, Denver, CO.
Kurt G BeamDepartment of Physiology and Biophysics, University of Colorado Denver Anschutz Medical Campus, Denver, CO.
Symeon PapadopoulosInstitute of Vegetative Physiology, University Hospital of Cologne, Cologne, Germany symeon.papadopoulos@uni-koeln.de.ORCID 0000-0002-0708-7431
University of Colorado Anschutz Medical Campus · USUniversity Hospital Cologne · DE

Funding

SIGNALING BETWEEN CALCIUM CHANNELSP01AR044750 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI ALLEN, PAUL D · 1997 to 2006
$9.3M
Regulation of Membrane ExcitabilityR01AR055104 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI BEAM, KURT G · 2008 to 2012
$3.1M
Regulation of Membrane ExcitabilityR01AR070298 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI BEAM, KURT G · 2016 to 2020
$2.0M
NIAMS NIH HHS P01 AR044750NIAMS NIH HHS R01 AR055104NIAMS NIH HHS R01 AR070298
6 · The paper itself

Abstract

The type 1 ryanodine receptor (RyR1) in skeletal muscle is a homotetrameric protein that releases Ca

Indexed as

Signal TransductionAction PotentialsAnimalsBinding SitesCalciumCalcium Channels, L-TypeCell LineCell MembraneCells, CulturedHumansMiceMuscle Fibers, SkeletalProtein BindingProtein MultimerizationProtein TransportRabbitsCACNA1S protein, mouseCalciumCalcium Channels, L-TypeRyanodine Receptor Calcium Release Channel

Identifiers

PMID29284662
PMCPMC5806685
OpenAlexW2779082875

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.