Evidence map›Paper›PMID 29284556›Full record

ArticleUltrasound in medicine & biology2018

Ultrasound Characterization of Bone Demineralization Using a Support Vector Machine.

Max Denis, Leighton Wan, Mostafa Fatemi, Azra Alizad

Abstract read
In one paragraph

Article in Ultrasound in medicine & biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Max DenisDepartment of Radiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA. Electronic address: denis.max@pnlsciences.com.
Leighton WanDepartment of Bioengineering, Stanford University, Stanford, California, USA.
Mostafa FatemiDepartment of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Azra AlizadDepartment of Radiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA; Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

Funding

Combined Acoustic Imaging and Viscoelastic Parameters Estimation in Breast CancerR01CA148994 · NCI · MAYO CLINIC ROCHESTER · PI ALIZAD, AZRA · 2011 to 2015
$2.4M
NCI NIH HHS R01 CA148994
6 · The paper itself

Abstract

We propose an ultrasound-guided remote measurement technique, utilizing an acoustic radiation force beam as our excitation source and a receiving hydrophone, to assess non-invasively a bone's mechanical properties. Features, such as velocity, were extracted from the acoustic pressure received from the bone surface. The typical velocity of an intact bone (3540 m/s) was higher in comparison to that of a demineralized bone (2231 m/s). According to the receiver operating characteristic curve, the optimal velocity cutoff value of ≥3096 m/s yields 80% sensitivity and 82.61% specificity between intact and demineralized bone. Utilizing a support vector machine, the hours of bone demineralization were successfully classified with maximum accuracy >80% using 18% training data. The results indicate the potential application of our proposed technique and support vector machine for monitoring bone mechanical properties.

Indexed as

Support Vector MachineAnimalsBone and BonesBone Demineralization, PathologicDisease Models, AnimalElasticity Imaging TechniquesImage Processing, Computer-AssistedPhantoms, ImagingRabbitsReproducibility of ResultsSensitivity and SpecificityAcoustic radiation forceBoneDemineralizationQuantitative ultrasoundSupport vector machines

Identifiers

PMID29284556
PMCPMC5801199

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.