ArticleBMC neurology2017
The relationship between lower limb muscle volume and body mass in ambulant individuals with bilateral cerebral palsy.
Article in BMC neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Human lower leg muscles grow asynchronously.Journal of anatomy · 2024Article
- Increased Upper Extremity Muscle Mass in Ambulatory Children with Cerebral Palsy.Life (Basel, Switzerland) · 2024Article
- Application of Virtual Reality-Assisted Exergaming on the Rehabilitation of Children with Cerebral Palsy: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
- A comprehensive normative reference database of muscle morphology in typically developing children aged 3-18 years-a cross-sectional ultrasound study.Journal of anatomy · 2023Article
- Morphological Medial Gastrocnemius Muscle Growth in Ambulant Children with Spastic Cerebral Palsy: A Prospective Longitudinal Study.Journal of clinical medicine · 2023Article
- How mechanics of individual muscle-tendon units define knee and ankle joint function in health and cerebral palsy-a narrative review.Frontiers in bioengineering and biotechnology · 2023Review
- Multi-level personalization of neuromusculoskeletal models to estimate physiologically plausible knee joint contact forces in children.Biomechanics and modeling in mechanobiology · 2022Article
- The Effect of a Horse-Riding Simulator with Virtual Reality on Gross Motor Function and Body Composition of Children with Cerebral Palsy: Preliminary Study.Sensors (Basel, Switzerland) · 2022Article
- Typical m. triceps surae morphology and architecture measurement from 0 to 18 years: A narrative review.Journal of anatomy · 2022Review
- Relation of Musculoskeletal Strength and Function to Postural Stability in Ambulatory Adults With Cerebral Palsy.Archives of rehabilitation research and clinical translation · 2020Article
- Soleus muscle weakness in cerebral palsy: Muscle architecture revealed with Diffusion Tensor Imaging.PloS one · 2019Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIndividuals with cerebral palsy have smaller muscle volumes normalised to body mass than their typically developing peers. The aim of this study is to investigate the relationship between lower limb muscle volume and body mass in young people with bilateral cerebral palsy and their typically developing peers.
methodsTwenty-five participants with bilateral cerebral palsy (aged 14.7±3.0 years, GMFCS level I-III) and 25 of their typically developing peers (aged 16.8±3.3 years) took part in this study. None of the participants had undergone orthopaedic surgery, botulinum toxin injections, or serial casting in the previous year. All participants underwent magnetic resonance imaging of both lower limbs. Nine major muscles of each lower limb were individually manually segmented and the muscle volumes calculated.
resultsBody mass and total lower limb muscle volume were significantly linearly related in both the cerebral palsy (R
conclusionsThis cross-sectional study suggests that the increase in size of lower limb muscles relative to body mass is reduced in adolescents and young adults with cerebral palsy. Longitudinal studies are required to further investigate altered muscle growth trajectories in this group and their impact on long-term mobility.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.