Evidence map›Paper›PMID 29284417›Full record

ArticleBMC medical research methodology2017

Abstract analysis method facilitates filtering low-methodological quality and high-bias risk systematic reviews on psoriasis interventions.

Francisco Gómez-García, Juan Ruano, Macarena Aguilar-Luque, Patricia Alcalde-Mellado, Jesús Gay-Mimbrera, José Luis Hernández-Romero, Juan Luis Sanz-Cabanillas, Beatriz Maestre-López, Marcelino González-Padilla, Pedro J Carmona-Fernández and 2 more

Abstract read
In one paragraph

Article in BMC medical research methodology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Quality of systematic reviews and meta-analyses in dermatology.Cochrane evidence synthesis and methods · 2024
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Francisco Gómez-GarcíaDepartment of Dermatology, Reina Sofía University Hospital, Menendez Pidal Ave, Córdoba, 14005, Spain.
Juan RuanoDepartment of Dermatology, Reina Sofía University Hospital, Menendez Pidal Ave, Córdoba, 14005, Spain. juanruanoruiz@mac.com.
Macarena Aguilar-LuqueDepartment of Dermatology, Reina Sofía University Hospital, Menendez Pidal Ave, Córdoba, 14005, Spain.
Patricia Alcalde-MelladoSchool of Medicine, University of Córdoba, Menendez Pidal Ave, Córdoba, 14005, Spain.
Jesús Gay-MimbreraIMIBIC/Reina Sofía University Hospital/UNiversity of Córdoba, Menendez Pidal Ave, Córdoba, 14005, Spain.
José Luis Hernández-RomeroDepartment of Dermatology, Reina Sofía University Hospital, Menendez Pidal Ave, Córdoba, 14005, Spain.
Juan Luis Sanz-CabanillasDepartment of Dermatology, Reina Sofía University Hospital, Menendez Pidal Ave, Córdoba, 14005, Spain.
Beatriz Maestre-LópezSchool of Medicine, University of Córdoba, Menendez Pidal Ave, Córdoba, 14005, Spain.
Marcelino González-PadillaDepartment of Dermatology, Reina Sofía University Hospital, Menendez Pidal Ave, Córdoba, 14005, Spain.
Pedro J Carmona-FernándezIMIBIC/Reina Sofía University Hospital/UNiversity of Córdoba, Menendez Pidal Ave, Córdoba, 14005, Spain.
Antonio Vélez García-NietoDepartment of Dermatology, Reina Sofía University Hospital, Menendez Pidal Ave, Córdoba, 14005, Spain.
Beatriz Isla-TejeraIMIBIC/Reina Sofía University Hospital/UNiversity of Córdoba, Menendez Pidal Ave, Córdoba, 14005, Spain.

Funding

Instituto de Salud Carlos III ICI1400136
6 · The paper itself

Abstract

backgroundArticle summaries' information and structure may influence researchers/clinicians' decisions to conduct deeper full-text analyses. Specifically, abstracts of systematic reviews (SRs) and meta-analyses (MA) should provide structured summaries for quick assessment. This study explored a method for determining the methodological quality and bias risk of full-text reviews using abstract information alone.

methodsSystematic literature searches for SRs and/or MA about psoriasis were undertaken on MEDLINE, EMBASE, and Cochrane database. For each review, quality, abstract-reporting completeness, full-text methodological quality, and bias risk were evaluated using Preferred Reporting Items for Systematic Reviews and Meta-analyses for abstracts (PRISMA-A), Assessing the Methodological Quality of Systematic Reviews (AMSTAR), and ROBIS tools, respectively. Article-, author-, and journal-derived metadata were systematically extracted from eligible studies using a piloted template, and explanatory variables concerning abstract-reporting quality were assessed using univariate and multivariate-regression models. Two classification models concerning SRs' methodological quality and bias risk were developed based on per-item and total PRISMA-A scores and decision-tree algorithms. This work was supported, in part, by project ICI1400136 (JR). No funding was received from any pharmaceutical company.

resultsThis study analysed 139 SRs on psoriasis interventions. On average, they featured 56.7% of PRISMA-A items. The mean total PRISMA-A score was significantly higher for high-methodological-quality SRs than for moderate- and low-methodological-quality reviews. SRs with low-bias risk showed higher total PRISMA-A values than reviews with high-bias risk. In the final model, only 'authors per review > 6' (OR: 1.098; 95%CI: 1.012-1.194), 'academic source of funding' (OR: 3.630; 95%CI: 1.788-7.542), and 'PRISMA-endorsed journal' (OR: 4.370; 95%CI: 1.785-10.98) predicted PRISMA-A variability. Reviews with a total PRISMA-A score < 6, lacking identification as SR or MA in the title, and lacking explanation concerning bias risk assessment methods were classified as low-methodological quality. Abstracts with a total PRISMA-A score ≥ 9, including main outcomes results and explanation bias risk assessment method were classified as having low-bias risk.

conclusionsThe methodological quality and bias risk of SRs may be determined by abstract's quality and completeness analyses. Our proposal aimed to facilitate synthesis of evidence evaluation by clinical professionals lacking methodological skills. External validation is necessary.

Indexed as

Review Literature as TopicAbstracting and IndexingBiasHumansMeta-Analysis as TopicPeriodicals as TopicPsoriasisPublishingQuality ControlResearch DesignResearch ReportRisk FactorsAbstract readabilityAMSTARDecision treesMethodological qualityPRISMA for abstractsPsoriasisQuality of reportingSystematic review

Identifiers

PMID29284417
PMCPMC5747101

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.