Evidence map›Paper›PMID 29283397›Full record

ReviewToxins2017

Ultrasound Guidance for Botulinum Neurotoxin Chemodenervation Procedures.

Katharine E Alter, Barbara I Karp

Abstract readReview
In one paragraph

Review in Toxins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Anatomy, Etiology, Management, and Medico-Legal Implications of Botulinum-induced Blepharoptosis.Current reviews in clinical and experimental pharmacology · 2025
    Review
  16. Article
  17. Article
  18. Canadian Physicians' Use of Ultrasound in Spasticity Treatment: A National Cross-Sectional Survey.Archives of rehabilitation research and clinical translation · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Katharine E AlterFunctional and Applied Biomechanics Section, Rehabilitation Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20892-1604, USA. kalter@cc.nih.gov.ORCID 0000-0002-5405-2143
Barbara I KarpCombined Neurosciences IRB, National Institutes of Health, Bethesda, MD 20892-1604, USA. karpb@ninds.nih.gov.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Injections of botulinum neurotoxins (BoNTs) are prescribed by clinicians for a variety of disorders that cause over-activity of muscles; glands; pain and other structures. Accurately targeting the structure for injection is one of the principle goals when performing BoNTs procedures. Traditionally; injections have been guided by anatomic landmarks; palpation; range of motion; electromyography or electrical stimulation. Ultrasound (US) based imaging based guidance overcomes some of the limitations of traditional techniques. US and/or US combined with traditional guidance techniques is utilized and or recommended by many expert clinicians; authors and in practice guidelines by professional academies. This article reviews the advantages and disadvantages of available guidance techniques including US as well as technical aspects of US guidance and a focused literature review related to US guidance for chemodenervation procedures including BoNTs injection.

Indexed as

UltrasonographyAnimalsArtifactsBotulinum ToxinsHumansInjectionsNerve BlockNeurotoxinsPractice Guidelines as TopicBotulinum ToxinsNeurotoxinsanatomic localizationbotulinum neurotoxinbotulinum toxinchemodenervationelectrical stimulationelectromyographyguidancemotor pointsultrasound

Identifiers

PMID29283397
PMCPMC5793105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.