ArticleIndian journal of ophthalmology2018
Results of simple limbal epithelial transplantation in unilateral ocular surface burn.
Article in Indian journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Outcomes of surgical interventions for the treatment of limbal stem cell deficiency.The Indian journal of medical research · 2021Pooled it
- Outcomes of Limbal Stem Cell Transplant: A Meta-analysis.JAMA ophthalmology · 2020Pooled it
- Diagnostic criteria for limbal stem cell deficiency before surgical intervention-A systematic literature review and analysis.Survey of ophthalmologyPooled it
- Midterm results after allogeneic simple limbal epithelial transplantation from deceased-donor eyes in patients with persistent corneal epithelial defects due to limbal stem cell deficiency.Acta ophthalmologica · 2025Article
- Review
- Autologous simple limbal stem cell transplantation with conjunctival autograft in chronic unilateral total LSCD with severe symblepharon due to severe alkali burn.BMJ case reports · 2024Article
- In Vivo Contactless, Cellular-Resolution Imaging of the Healthy and Pathological Human Limbus With 250-kHz Point-Scanning SD-OCT.Translational vision science & technology · 2024Article
- The Multifold Etiologies of Limbal Stem Cell Deficiency: A Comprehensive Review on the Etiologies and Additional Treatment Options for Limbal Stem Cell Deficiency.Journal of clinical medicine · 2023Review
- Economic, clinical and social impact of simple limbal epithelial transplantation for limbal stem cell deficiency.The British journal of ophthalmology · 2022Review
- Demographic, Clinical Profile and Management Outcomes of Ocular Chemical Injuries in Saudi Children.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Innovative technique of mini-simple limbal epithelial transplantation in pediatric patients.Indian journal of ophthalmology · 2021Article
- Fibrin-Plasma Rich in Growth Factors Membrane for the Treatment of a Rabbit Alkali-Burn Lesion.International journal of molecular sciences · 2021Article
- Clinical outcomes of modified simple limbal epithelial transplantation for limbal stem cell deficiency in Chinese population: a retrospective case series.Stem cell research & therapy · 2021Article
- Mini-Review: Regenerating the Corneal Epithelium With Simple Limbal Epithelial Transplantation.Frontiers in medicine · 2021Review
- Surgical Management of Unilateral Partial Limbal Stem Cell Deficiency: Conjunctival Autografts versus Simple Limbal Epithelial Transplantation.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Recent Advances in Stem Cell Therapy for Limbal Stem Cell Deficiency: A Narrative Review.Ophthalmology and therapy · 2020Review
- In Vivo Confocal Microscopy of the Corneal-Conjunctival Transition in the Evaluation of Epithelial Renewal after SLET.Journal of clinical medicine · 2020Article
- Reappearance of limbal pigmentation post-simple limbal epithelial transplant.Indian journal of ophthalmology · 2020Article
- Simple limbal epithelial transplantation: Current status and future perspectives.Stem cells translational medicine · 2020Review
- Corneal injury: Clinical and molecular aspects.Experimental eye research · 2019Review
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to report the long-term outcomes of autologous Simple Limbal Epithelial Transplantation (SLET) performed for unilateral limbal stem cell deficiency (LSCD) following chemical burn at a tertiary eye center in North India.
methodsThis was a single-center prospective interventional case series of patients who developed unilateral LSCD after suffering from ocular surface burns and who underwent SLET between October 2012 and May 2016 with a follow-up period of at least 6 months. The primary outcome measure was restoration of a completely epithelized, stable, and avascular corneal surface. The secondary outcome measure was percentage of eyes, which reported visual gain.
resultsThe study included 30 eyes of 30 patients, 18 adults and 12 children, at a median follow-up of 1.1 years (range: 6 months to 3.5 years), 21 of 30 eyes (70%; 95% confidence interval, 53.6%-86.2%) maintained successful outcome. Visual acuity gain was seen in 71.4% of successful cases. The clinical factors associated with failure were identified as acid injury, severe symblepharon at the time of presentation, and SLET combined with penetrating keratoplasty (PK).
conclusionAutologous SLET is an effective limbal cell transplantation technique for the treatment of unilateral LSCD. It is especially beneficial for centers where cell cultivation laboratory is unavailable. Presence of severe symblepharon, which requires PK peroperatively , has poor outcome.
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