Evidence map›Paper›PMID 29282737›Full record

ArticleThe Journal of pathology2018

From bad to worse: when lung cancer complicates idiopathic pulmonary fibrosis.

Stephen B Strock, Jonathan K Alder, Daniel J Kass

Open access · greenAbstract readComment
In one paragraph

Article in The Journal of pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Stephen B StrockDorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, University of Pittsburgh, Pittsburgh, PA, USA.
Jonathan K AlderDorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, University of Pittsburgh, Pittsburgh, PA, USA.
Daniel J KassDorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0001-6597-7830
University of Pittsburgh · US

Funding

Twist1 subphenotypes and pulmonary fibrosisR01HL126990 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KASS, DANIEL J · 2015 to 2019
$1.9M
Mechanisms of Teleomere-Mediated EmphysemaR00HL113105 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALDER, JONATHAN K. · 2014 to 2016
$743k
NHLBI NIH HHS R00 HL113105NHLBI NIH HHS R01 HL126990
6 · The paper itself

Abstract

Patients with idiopathic pulmonary fibrosis have a significantly increased risk for the development of lung cancer. The morbidity and mortality of this disease combination are substantial, and, unfortunately, there are currently few data to help guide clinicians in its diagnosis and treatment. In a recent issue of this journal, Hwang et al presented one of the first studies to evaluate lung cancer in patients with idiopathic pulmonary fibrosis at the molecular level. They demonstrate variants in regulators of the cell cycle, which are known to be important in malignant transformation and may also be important in the pathogenesis of idiopathic pulmonary fibrosis. Further understanding of the pathogenic overlap between lung cancer and idiopathic pulmonary fibrosis could help point the direction to specific diagnostic modalities and targeted treatment of both conditions in the future. Copyright © 2017 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

Indexed as

Idiopathic Pulmonary FibrosisLung NeoplasmsMycobacterium tuberculosisAntimicrobial Cationic PeptidesCathelicidinsHumansUnited KingdomAntimicrobial Cationic PeptidesCathelicidinsidiopathic pulmonary fibrosislung cancermicroRNAtelomere

Identifiers

PMID29282737
PMCPMC6491351
OpenAlexW2780632913

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.