ReviewHead and neck pathology2018
Sinonasal Tract Solitary Fibrous Tumor: A Clinicopathologic Study of Six Cases with a Comprehensive Review of the Literature.
Review in Head and neck pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Solitary fibrous tumor of the oral cavity: a systematic review of the literature and a new clinicopathologic case report.Frontiers in oral health · 2026Pooled it
- Solitary fibrous tumor: an updated review.Journal of pathology and translational medicine · 2026Article
- Article
- The Solitary Fibrous Tumor, the Chameleon of the Head and Neck Region-Clinical, Epidemiological, and Histopathological Aspects.Diagnostics (Basel, Switzerland) · 2025Article
- Solitary fibrous tumor of the nasal septum: a case report and literature review.Journal of surgical case reports · 2025Article
- Solitary fibrous tumors from A to Z: a pictorial review with radiologic-pathologic correlation.Insights into imaging · 2025Article
- Xanthogranulomatous epithelial tumors/keratin-positive giant cell-rich tumors involving the head and neck: report of seven cases and review of the literature.Virchows Archiv : an international journal of pathology · 2024Review
- Benign Spindle Cell Lesion of the Nasal Cavity: A Rare Presentation of Solitary Fibrous Tumor.Cureus · 2024Article
- Article
- Spindle Cell Tumors of the Sinonasal Tract: A Diagnostic Update with Focus on Ancillary Workup.Head and neck pathology · 2024Review
- Review
- A Rare Case of Solitary Fibrosus Tumor (SFT) of the Nasal Septum.Iranian journal of otorhinolaryngology · 2023Article
- Translocations and Gene Fusions in Sinonasal Malignancies.Current oncology reports · 2023Review
- Top 10 Significant Spindled Head and Neck Lesions to Scrutinze.Head and neck pathology · 2023Review
- Article
- [Research progress of intraspinal solitary fibrous tumor].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023Review
- Primary intranasal perivascular wall tumors in 2 cats.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2023Article
- A Rare Occurrence of an Extensive Sino-Nasal Solitary Fibrous Tumour.Iranian journal of otorhinolaryngology · 2022Article
- Rare Case of Solitary Nasal Fibrous Tumor Eroding Skull-Base.Asian journal of neurosurgery · 2022Article
- Tumours of Nasal Septum: A Retrospective Study of 32 Patients.International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Solitary fibrous tumors (SFTs) are well recognized in the head and neck region, but rarely arise in the sinonasal tract (SNT). Six primary SNT SFTs were identified in the files of Southern California Permanente Medical Group between 2006 and 2017. The patients included five males and one female ranging in age from 33 to 72 years (mean 52 years), most of whom presented clinically with nasal obstruction. Three tumors involved the nasal cavity alone, one involved the paranasal sinuses, and two involved both the nasal cavity and paranasal sinuses. Histologically, the tumors were characterized by a variably cellular proliferation of cytologically bland spindle cells within a collagenous stroma with prominent interspersed branching vessels. Mitotic activity was low (range 0-2 per 10 high power fields) and there was no evidence of pleomorphism or tumor necrosis. Surface ulceration was noted. By immunohistochemistry, the lesional cells were positive for CD34, STAT6 and bcl-2. Clinical follow up information was available for all patients (range 32-102 months; mean 72 months). There were no recurrences or metastases and all were alive with no evidence of disease at last follow-up. SFTs rarely affect the SNT, but should be considered in the differential diagnosis of SNT mesenchymal lesions. Immunohistochemical expression of STAT6 can aid in diagnosis and separation of SFT from other spindle cell lesions occurring at this anatomic site. In combination with cases reported in the literature, primary SNT SFT behave in an indolent manner with conservative treatment.
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