ArticleRice (New York, N.Y.)2017
OsLAP6/OsPKS1, an orthologue of Arabidopsis PKSA/LAP6, is critical for proper pollen exine formation.
Article in Rice (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed, 91 citations in OpenAlex.
- Premeiotic chromatin states orchestrate gene expression during male gametogenesis in rice.Genome biology · 2026Article
- OsMT2b Regulates Pollen Development and ROS Homeostasis in a Photoperiod-Dependent Manner.Plant biotechnology journal · 2026Article
- Key genes and molecular mechanisms responsible for male sterility revealed by transcriptome analysis in cotton.Plant cell reports · 2025Article
- Article
- Loss of phytochromobilin synthase activity leads to larger seeds with higher protein content in soybean.BMC plant biology · 2025Article
- Genetic and molecular mechanisms underlying the male sterility in rice.Journal of applied genetics · 2025Review
- Disruption of the endoplasmic reticulum-localized fatty acyl-ACP thioesterase IPF1 caused partial male sterility in rice.Plant molecular biology · 2025Article
- The molecular mechanism and utilization of ZmMs7-mediated dominant nuclear sterility inFrontiers in plant science · 2025Article
- Identification of the new allele ptc1-2 and analysis of the regulatory role of PTC1 gene in rice anther development.BMC plant biology · 2024Article
- Hybrid Rice Production: A Worldwide Review of Floral Traits and Breeding Technology, with Special Emphasis on China.Plants (Basel, Switzerland) · 2024Review
- Dysfunction of duplicated pair rice histone acetyltransferases causes segregation distortion and an interspecific reproductive barrier.Nature communications · 2024Article
- BOTRYOID POLLEN 1 regulates ROS-triggered PCD and pollen wall development by controlling UDP-sugar homeostasis in rice.The Plant cell · 2023Article
- CRISPR/Cas9-mediated disruption of CjACOS5 confers no-pollen formation on sugi trees (Cryptomeria japonica D. Don).Scientific reports · 2023Article
- An uncharacterized protein NY1 targets EAT1 to regulate anther tapetum development in polyploid rice.BMC plant biology · 2022Article
- SWOLLEN TAPETUM AND STERILITY 1 is required for tapetum degeneration and pollen wall formation in rice.Plant physiology · 2022Article
- An ortholog of the MADS-box gene SEPALLATA3 regulates stamen development in the woody plant Jatropha curcas.Planta · 2022Article
- Overexpression of sesame polyketide synthase A leads to abnormal pollen development in Arabidopsis.BMC plant biology · 2022Article
- Genetic mapping high protein content QTL from soybean 'Nanxiadou 25' and candidate gene analysis.BMC plant biology · 2021Article
- OsMS188 Is a Key Regulator of Tapetum Development and Sporopollenin Synthesis in Rice.Rice (New York, N.Y.) · 2021Article
- Transcriptome Analysis Reveals Photoperiod-Associated Genes Expressed in Rice Anthers.Frontiers in plant science · 2021Article
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Authors and funding
17 authors at 2 institutions in 1 country.
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Abstract
backgroundMale fertility is crucial for rice yield, and the improvement of rice yield requires hybrid production that depends on male sterile lines. Although recent studies have revealed several important genes in male reproductive development, our understanding of the mechanisms of rice pollen development remains unclear.
resultsWe identified a rice mutant oslap6 with complete male sterile phenotype caused by defects in pollen exine formation. By using the MutMap method, we found that a single nucleotide polymorphism (SNP) variation located in the second exon of OsLAP6/OsPKS1 was responsible for the mutant phenotype. OsLAP6/OsPKS1 is an orthologous gene of Arabidopsis PKSA/LAP6, which functions in sporopollenin metabolism. Several other loss-of-function mutants of OsLAP6/OsPKS1 generated by the CRISPR/Cas9 genomic editing tool also exhibited the same phenotype of male sterility. Our cellular analysis suggested that OsLAP6/OsPKS1 might regulate pollen exine formation by affecting bacula elongation. Expression examination indicated that OsLAP6/OsPKS1 is specifically expressed in tapetum, and its product is localized to the endoplasmic reticulum (ER). Protein sequence analysis indicated that OsLAP6/OsPKS1 is conserved in land plants.
conclusionsOsLAP6/OsPKS1 is a critical molecular switch for rice male fertility by participating in a conserved sporopollenin precursor biosynthetic pathway in land plants. Manipulation of OsLAP6/OsPKS1 has potential for application in hybrid rice breeding.
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