Evidence map›Paper›PMID 29282506›Full record

Observational studyWorld journal of surgery2018

The Use of a Pre-operative Carbohydrate Drink in Patients with Diabetes Mellitus: A Prospective, Non-inferiority, Cohort Study.

Michael R Laffin, Shuai Li, Rondald Brisebois, Peter A Senior, Haili Wang

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in World journal of surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Guideline
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  5. Trial
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  14. Observational
  15. Perioperative management in gynecological surgery based on the ERAS program.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Michael R LaffinDepartment of Surgery, 2D, Walter C Mackenzie Health Sciences Centre, University of Alberta, 8440 - 112 Street, Edmonton, AB, T6G 2R3, Canada. mlaffin@ualberta.ca.
Shuai LiFaculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Rondald BriseboisDepartment of Surgery, 2D, Walter C Mackenzie Health Sciences Centre, University of Alberta, 8440 - 112 Street, Edmonton, AB, T6G 2R3, Canada.
Peter A SeniorDivision of Endocrinology, University of Alberta, Edmonton, AB, Canada.
Haili WangDepartment of Surgery, 2D, Walter C Mackenzie Health Sciences Centre, University of Alberta, 8440 - 112 Street, Edmonton, AB, T6G 2R3, Canada.
University of Alberta · CAHealth Sciences Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPre-operative fasting leads to insulin resistance and increased metabolic stress in non-diabetic patients. Consumption of a carbohydrate drink may alleviate these deleterious effects. Patients with diabetes mellitus represent over 15% of the surgical population, yet concerns over hyperglycemia and aspiration have excluded patients with diabetes mellitus from studies assessing the utility of pre-operative carbohydrate drinks.

objectiveTo assess for a clinically significant increase in pre-operative blood glucose concentration (defined as >2 mmol/L) in patients with diabetes consuming a pre-operative carbohydrate drink.

methodsA prospective observational non-inferiority cohort study of 106 subjects with diabetes mellitus was undertaken to assess the effect of consuming a pre-operative carbohydrate drink in surgical patients. All patients with diabetes mellitus undergoing surgery (including but not limited to cardiac, neurologic, urologic, and general surgical procedures) were enrolled. Subjects were instructed to consume two carbohydrate-rich drinks, one before sleeping the evening prior to surgery and another on the day of surgery.

resultsIn total, 43% of subjects were fully compliant with the pre-operative carbohydrate drink regimen. There were no significant differences between the fully compliant and non-compliant subjects with respect to baseline characteristics. Consumption of a pre-operative carbohydrate drink was determined to be non-inferior to fasting in terms of pre-operative blood glucose concentration (absolute difference 0.23 mmol/L, 95% CI: -1.00 to 1.45 mmol/L, p

conclusionsThese findings function as a step toward ensuring pre-operative carbohydrate drinks are safe in patients with diabetes undergoing surgery.

Indexed as

Preoperative CareAdultAgedBlood GlucoseDiabetes MellitusDietary CarbohydratesDrinkingFastingFemaleHumansMaleMiddle AgedProspective StudiesBlood GlucoseDietary Carbohydrates

Identifiers

PMID29282506
OpenAlexW2777903690

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.