Evidence map›Paper›PMID 29282365›Full record

ArticleThe pharmacogenomics journal2019

Genetic and clinic predictors of new onset diabetes mellitus after transplantation.

Núria Saigi-Morgui, Lina Quteineh, Pierre-Yves Bochud, Severine Crettol, Zoltán Kutalik, Nicolas J Mueller, Isabelle Binet, Christian Van Delden, Jürg Steiger, Paul Mohacsi and 5 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in The pharmacogenomics journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Núria Saigi-MorguiUnit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Lausanne University Hospital, Prilly, Switzerland.
Lina QuteinehUnit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Lausanne University Hospital, Prilly, Switzerland.
Pierre-Yves BochudService of Infectious Diseases, Lausanne University Hospital, Lausanne, Switzerland.
Severine CrettolUnit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Lausanne University Hospital, Prilly, Switzerland.ORCID http://orcid.org/0000-0003-3790-7194
Zoltán KutalikInstitute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital, Lausanne, Switzerland.
Nicolas J MuellerDivision of Infectious Diseases and Hospital Epidemiology, University Hospital, Zurich, Switzerland.
Isabelle BinetService of Nephrology and Transplantation Medicine, Kantonsspital, St Gallen, Switzerland.
Christian Van DeldenService of Infectious Diseases, University Hospital, Geneva, Switzerland.
Jürg SteigerClinic of Transplantationimmunology and Neprhology, University Hospital, Basel, Switzerland.
Paul MohacsiSwiss Cardiovascular Center Bern, University Hospital, Bern, Switzerland.
Jean-Francois DufourDepartment of Clinical Pharmacology, University Hospital, Bern, Switzerland.
Paola M SoccalService of Pulmonary Medicine, University Hospital, Geneva, Switzerland.
Manuel PascualTransplant Center, Lausanne University Hospital, Lausanne, Switzerland.
Chin B EapUnit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Lausanne University Hospital, Prilly, Switzerland. chin.eap@chuv.ch.
Swiss Transplant Cohort Study

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New Onset Diabetes after Transplantation (NODAT) is a frequent complication after solid organ transplantation, with higher incidence during the first year. Several clinical and genetic factors have been described as risk factors of Type 2 Diabetes (T2DM). Additionally, T2DM shares some genetic factors with NODAT. We investigated if three genetic risk scores (w-GRS) and clinical factors were associated with NODAT and how they predicted NODAT development 1 year after transplantation. In both main (n = 725) and replication (n = 156) samples the clinical risk score was significantly associated with NODAT (OR

Indexed as

AdolescentAdultAgedCohort StudiesDiabetes MellitusFemaleGenotypeHumansIncidenceMaleMiddle AgedOrgan TransplantationProspective StudiesRisk FactorsYoung Adult

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.