Evidence map›Paper›PMID 29282309›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Identification of a Multipotent Progenitor Population in the Spleen That Is Regulated by NR4A1.

Melanie D Mumau, Ashley N Vanderbeck, Elizabeth D Lynch, Sophia B Golec, Stephen G Emerson, Jennifer A Punt

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Role of Nuclear Receptors in Controlling Erythropoiesis.International journal of molecular sciences · 2022
    Review
  3. Article
  4. Review
  5. Neutrophils in cancer carcinogenesis and metastasis.Journal of hematology & oncology · 2021
    Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Melanie D MumauHerbert Irving Comprehensive Cancer Research Center, Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032 melanie.mumau@gmail.com.ORCID 0000-0003-2145-8347
Ashley N VanderbeckHerbert Irving Comprehensive Cancer Research Center, Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032.
Elizabeth D LynchHerbert Irving Comprehensive Cancer Research Center, Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032.
Sophia B GolecHerbert Irving Comprehensive Cancer Research Center, Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032.
Stephen G EmersonHerbert Irving Comprehensive Cancer Research Center, Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032.ORCID 0000-0002-3582-9340
Jennifer A PuntHerbert Irving Comprehensive Cancer Research Center, Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032.ORCID 0000-0002-4439-5628
Columbia University Irving Medical Center · US

Funding

Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Parisa Tehranifar · 1985 to 2026
$115.3M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007170 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BRASS, LAWRENCE F · 1985 to 2022
$54.0M
VMD-PhD Training in Infectious Disease-Related ResearchT32AI070077 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Michael Lee Atchison · 2008 to 2026
$3.5M
Columbia University Graduate Training Program in Microbiology and ImmunologyT32AI106711 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Nicholas Arpaia, Uttiya Basu · 2014 to 2026
$2.1M
NCI NIH HHS P30 CA013696NIAID NIH HHS T32 AI070077NIAID NIH HHS T32 AI106711NIGMS NIH HHS T32 GM007170
6 · The paper itself

Abstract

The developmental fate of hematopoietic stem and progenitor cells is influenced by their physiological context. Although most hematopoietic stem and progenitor cells are found in the bone marrow of the adult, some are found in other tissues, including the spleen. The extent to which the fate of stem cells is determined by the tissue in which they reside is not clear. In this study, we identify a new progenitor population, which is enriched in the mouse spleen, defined by cKit

Indexed as

AnimalsAntigens, CDCD24 AntigenErythropoiesisHematopoietic Stem CellsMiceMice, Inbred C57BLMice, KnockoutMyeloid CellsNuclear Receptor Subfamily 4, Group A, Member 1Proto-Oncogene Proteins c-kitReceptors, TransferrinSpleenThrombopoiesisAntigens, CDCD24 AntigenCd24a protein, mouseCD71 antigenNr4a1 protein, mouseNuclear Receptor Subfamily 4, Group A, Member 1Proto-Oncogene Proteins c-kitReceptors, Transferrin

Identifiers

PMID29282309
PMCPMC5793861
OpenAlexW2778324695

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.