Evidence map›Paper›PMID 29282061›Full record

ReviewBMC biology2017

The human microbiome in evolution.

Emily R Davenport, Jon G Sanders, Se Jin Song, Katherine R Amato, Andrew G Clark, Rob Knight

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 182 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
182citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

182 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Effect of Probiotics Therapy on Nonalcoholic Fatty Liver Disease.Computational and mathematical methods in medicine · 2022
    Pooled it
  6. The Role of Genital Tract Microbiome in Fertility: A Systematic Review.International journal of molecular sciences · 2021
    Pooled it
  7. Pooled it
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  9. Review
  10. Article
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  14. Humans as an extended phenotype of their microbiota.Theory in biosciences = Theorie in den Biowissenschaften · 2026
    Article
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122 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emily R DavenportDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
Jon G SandersDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Se Jin SongDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Katherine R AmatoDepartment of Anthropology, Northwestern University, Evanston, IL, USA.
Andrew G ClarkDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
Rob KnightDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.

Funding

Modeling Human Gut Microbiome Community Structure in Healthy and Diseased StatesF32DK109595 · NIDDK · CORNELL UNIVERSITY · PI DAVENPORT, EMILY · 2016 to 2018
$173k
Howard Hughes Medical InstituteNIDDK NIH HHS F32 DK109595
6 · The paper itself

Abstract

The trillions of microbes living in the gut-the gut microbiota-play an important role in human biology and disease. While much has been done to explore its diversity, a full understanding of our microbiomes demands an evolutionary perspective. In this review, we compare microbiomes from human populations, placing them in the context of microbes from humanity's near and distant animal relatives. We discuss potential mechanisms to generate host-specific microbiome configurations and the consequences of disrupting those configurations. Finally, we propose that this broader phylogenetic perspective is useful for understanding the mechanisms underlying human-microbiome interactions.

Indexed as

Biological EvolutionAnimalsGastrointestinal MicrobiomeHost SpecificityHumansMicrobiotaPhylogenyCodiversificationEvolutionHabitat filteringMicrobiomeTransmission

Identifiers

PMID29282061
PMCPMC5744394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.