Evidence map›Paper›PMID 29282034›Full record

ArticleBMC cancer2017

Outcome of breast cancer screening in Denmark.

Elsebeth Lynge, Martin Bak, My von Euler-Chelpin, Niels Kroman, Anders Lernevall, Nikolaj Borg Mogensen, Walter Schwartz, Adam Jan Wronecki, Ilse Vejborg

Abstract read
In one paragraph

Article in BMC cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  15. Breast MRI: an illustration of benign findings.The British journal of radiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elsebeth LyngeDepartment of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark. elsebeth@sund.ku.dk.ORCID 0000-0003-4785-5236
Martin BakDepartment of Pathology, Odense University Hospital, J. B. Winsløws Vej 15, 5000, Odense, Denmark.
My von Euler-ChelpinDepartment of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark.
Niels KromanDepartment of Breast Surgery, Copenhagen University Hospital Herlev, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Anders LernevallDepartment of Public Health Programmes, Randers Regional Hospital, Skovlyvej 15, 8930, Randers NØ, Denmark.
Nikolaj Borg MogensenRadiology Department, Ringsted Hospital, Bøllingsvej 30, 4100, Ringsted, Denmark.
Walter SchwartzMammography Centre, Odense University Hospital, J. B. Winsløws Vej 15, 5000, Odense, Denmark.
Adam Jan WroneckiRadiology Department, Aalborg Univeristy Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.
Ilse VejborgRadiology Department, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, 2200, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Denmark, national roll-out of a population-based, screening mammography program took place in 2007-2010. We report on outcome of the first four biennial invitation rounds.

methodsData on screening outcome were retrieved from the 2015 and 2016 national screening quality reports. We calculated coverage by examination; participation after invitation; detection-, interval cancer- and false-positive rates; cancer characteristics; sensitivity and specificity, for Denmark and for the five regions.

resultsAt the national level coverage by examination remained at 75-77%; lower in the Capital Region than in the rest of Denmrk. Detection rate was slightly below 1% at first screen, 0.6% at subsequent screens, and one region had some fluctuation over time. Ductal carcinoma in situ (DCIS) constituted 13-14% of screen-detected cancers. In subsequent rounds, 80% of screen-detected invasive cancers were node negative and 40% ≤10 mm. False-positive rate was around 2%; higher for North Denmark Region than for the rest of Denmark. Three out of 10 breast cancers in screened women were diagnosed as interval cancers.

conclusionsHigh coverage by examination and low interval cancer rate are required for screening to decrease breast cancer mortality. Two pioneer local screening programs starting in the 1990s were followed by a decrease in breast cancer mortality of 22-25%. Coverage by examination and interval cancer rate of the national program were on the favorable side of values from the pioneer programs. It appears that the implementation of a national screening program in Denmark has been successful, though regional variations need further evaluation to assure optimization of the program.

Indexed as

Outcome Assessment, Health CareAgedBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingDenmarkEarly Detection of CancerFemaleFollow-Up StudiesHumansMammographyMiddle AgedPrognosisSurvival RateBreast cancerDuctal carcinoma in situ.Mammography.Screening.

Identifiers

PMID29282034
PMCPMC5745763

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.