Evidence map›Paper›PMID 29281989›Full record

ArticleBMC infectious diseases2017

Necrotizing soft tissue infection: clinical characteristics and outcomes at a reconstructive center in Jilin Province.

Jing-Chun Zhao, Bo-Ru Zhang, Kai Shi, Xi Zhang, Chun-Hui Xie, Jian Wang, Qing-Hua Yu, Xin-Xin Gao, Lei Hong, Jia-Ao Yu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
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  9. [Conservation surgery and early rehabilitation in massive necrotizing fasciitis of the lower limbs]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2022
    Article
  10. Article
  11. Necrotizing Soft Tissue Infections: More than What Meets the Eye.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022
    Article
  12. [Necrotizing fasciitis of the extremities and trunk].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020
    Review
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jing-Chun ZhaoBurns and Plastic Reconstruction Unit, the First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, 130021, China.
Bo-Ru ZhangBurns and Plastic Reconstruction Unit, the First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, 130021, China.
Kai ShiBurns and Plastic Reconstruction Unit, the First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, 130021, China.
Xi ZhangBurns and Plastic Reconstruction Unit, the First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, 130021, China.
Chun-Hui XieBurns and Plastic Reconstruction Unit, the First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, 130021, China.
Jian WangBurns and Plastic Reconstruction Unit, the First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, 130021, China.
Qing-Hua YuBurns and Plastic Reconstruction Unit, the First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, 130021, China.
Xin-Xin GaoBurns and Plastic Reconstruction Unit, the First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, 130021, China.
Lei HongBurns and Plastic Reconstruction Unit, the First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, 130021, China.
Jia-Ao YuBurns and Plastic Reconstruction Unit, the First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, 130021, China. 84858892@qq.com.
First Hospital of Jilin University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the clinical characteristics and treatment outcomes in necrotizing fasciitis (NF) patients in a reconstructive unit in northeastern China.

methodsMedical records of patients diagnosed with and treated for NF in the extremities from November 2013 to December 2016 were retrospectively reviewed. Demographic data, clinical presentation, duration of signs and symptoms, location of infection, predisposing factors, causative microbiological organisms, laboratory risk indicator for necrotizing fasciitis (LRINEC) score, number of surgical debridements, length of hospital stay, treatments, and outcomes were recorded.

resultsA total of 39 consecutive patients were treated for severe NF (32 male and 7 female). Diabetes mellitus and blunt trauma were the most common risk factors (13 and 9 cases, respectively). The positive predictive value of the LRINEC score in NF diagnosis was 46.2%. Mean duration of signs and symptoms was 4.6 days. Staphylococcus aureus was the most commonly isolated bacteria (20 cases). All patients underwent their first debridement within 12 h of presentation (mean, 4.6 h). Mean number of surgical treatments was 2.8 (range, 2-5) per patient, including debridements. All patients survived, and mean length of hospital stay was 30.81 (range, 21-43) days. Three patients underwent limb amputation.

conclusionsIn our clinical experience, early detection and aggressive debridement are the cornerstones of NF treatment. Antibiotic therapy and intensive care support is essential in severe cases of NF. Anaerobic tissue culture and frozen section biopsy could be adopted as routine tests for diagnosis and decision-making in NF. These findings should inform clinical decisions about the treatment of individual patients with NF.

Indexed as

AdultChinaDebridementDiabetes ComplicationsFasciitis, NecrotizingFemaleHumansLength of StayMaleMiddle AgedRetrospective StudiesRisk FactorsSoft Tissue InfectionsStaphylococcus aureusTreatment OutcomeExtremityNecrotizing fasciitisSurgical debridementTreatment

Identifiers

PMID29281989
PMCPMC5745726
OpenAlexW2778746645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.