ArticlePloS one2017
Anti-inflammatory effect of Allium hookeri on carrageenan-induced air pouch mouse model.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 33 citations in OpenAlex.
- A randomized, double-blind, placebo-controlled crossover clinical trial to evaluate the anti-diabetic effects of Allium hookeri extract in the subjects with prediabetes.BMC complementary medicine and therapies · 2020Trial
- GC-MS profiling,Frontiers in chemistry · 2026Article
- Evaluation of Bioactive Compounds, Antioxidant Capacity, and Anti-Inflammatory Effects of Lipophilic and Hydrophilic Extracts of the Pericarp ofMolecules (Basel, Switzerland) · 2024Article
- Supplementary Effects ofPharmaceuticals (Basel, Switzerland) · 2023Article
- The Phytochemistry and Pharmacology ofMolecules (Basel, Switzerland) · 2022Review
- Korean Red Ginseng affects ovalbumin-induced asthma by modulating IL-12, IL-4, and IL-6 levels and the NF-κB/COX-2 and PGEJournal of ginseng research · 2021Article
- In vitro and in vivo anti-inflammatory activity and chemical composition of Renealmia petasites Gagnep.Inflammopharmacology · 2021Article
- Antibacterial, anti-inflammatory and peroxidase-mediated cyclooxygenase-1 inhibitory properties ofPharmaceutical biology · 2019Article
- Allium hookeri root extract regulates asthmatic changes through immunological modulation of Th1/Th2‑related factors in an ovalbumin‑induced asthma mouse model.Molecular medicine reports · 2019Article
- Potent antitumor property of Allium bakhtiaricum extracts.BMC complementary and alternative medicine · 2019Article
- Screening of NO Inhibitor Release Activity from Soft Coral Extracts Origin Palu Bay, Central Sulawesi, Indonesia.Anti-inflammatory & anti-allergy agents in medicinal chemistry · 2019Article
- Dietary Consumption on Glycemic Control Among Prediabetes: A Review of the Literature.SAGE open nursingReview
- Psoriasis-like Inflammation Induced in an Air-pouch Mouse Model.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammation is a commonly observed immune reaction, and rheumatoid arthritis is a particularly severe inflammatory disease. In this study, we used an air pouch mouse model to evaluate the anti-inflammatory potential of Allium hookeri, which has both been used as a culinary material and a traditional medicine in south-eastern Asia for many years. Allium hookeri suppressed typical symptoms of inflammation, such as condensation of the air pouch membrane, and inhibited the expression of several inducible proinflammatory cytokines such as IL-1β, IL-6, IL-13, and TNF-α. In order to determine the molecules modulating the inflammatory effect of carrageenan treatment, the components in Allium hookeri were analyzed by GC-MS, and linoleic acid, which have anti-inflammatory effect, was detected. From the results, we concluded that the anti-inflammatory effect of Allium hookeri might be attributed to linoleic acid, which could be promising candidates for anti-inflammatory drugs that have no adverse effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.