ArticlePloS one2017
Taxonomic differences of gut microbiomes drive cellulolytic enzymatic potential within hind-gut fermenting mammals.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 36 citations in OpenAlex.
- Ground squirrel coprolites preserve complex archives of ancient environmental DNA over 700,000 years.Nature communications · 2026Article
- Dietary drivers of gut microbiota diversity and function in wildlife of Wolong Nature Reserve: a metagenomic study.Current zoology · 2026Article
- PICRUSt2-SC: an update to the reference database used for functional prediction within PICRUSt2.Bioinformatics (Oxford, England) · 2025Article
- Gut microbiome reveals the trophic variation and significant adaption of three sympatric forest-dwelling ungulates on the eastern Qinghai-Xizang Plateau.BMC microbiology · 2025Article
- Recent genetic drift in the co-diversified gut bacterial symbionts of laboratory mice.Nature communications · 2025Article
- Spatiotemporal differences induced changes in the structure and function of the gut microbiota in an endangered ungulate.Animal microbiome · 2024Article
- The Microbiota of the Outer Gut Mucus Layer of the Migrating Northeast Arctic Cod (Microorganisms · 2024Article
- Article
- Recent genetic drift in the co-diversified gut bacterial symbionts of laboratory mice.bioRxiv : the preprint server for biology · 2024Article
- Effect of Red-Beetroot-Supplemented Diet on Gut Microbiota Composition and Metabolite Profile of Weaned Pigs-A Pilot Study.Animals : an open access journal from MDPI · 2023Article
- Irinotecan-gut microbiota interactions and the capability of probiotics to mitigate Irinotecan-associated toxicity.BMC microbiology · 2023Article
- From defaults to databases: parameter and database choice dramatically impact the performance of metagenomic taxonomic classification tools.Microbial genomics · 2023Article
- Contrasting gut microbiota in captive Eurasian otters (Lutra lutra) by age.Archives of microbiology · 2021Article
- Effects of laboratory domestication on the rodent gut microbiome.ISME communications · 2021Article
- Effect of Geography and Captivity on Scat Bacterial Communities in the Imperiled Channel Island Fox.Frontiers in microbiology · 2021Article
- Egyptian Mongoose (Microorganisms · 2020Article
- Gut Microbiomes Differ Among Dietary Types and Stool Consistency in the Captive Red Wolf (Frontiers in microbiology · 2020Article
- Identification of Gastrointestinal Microbiota in Hawaiian Green Turtles (Evolutionary bioinformatics online · 2020Article
- Characterization of novel lignocellulose-degrading enzymes from the porcupine microbiome using synthetic metagenomics.PloS one · 2019Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Host diet influences the diversity and metabolic activities of the gut microbiome. Previous studies have shown that the gut microbiome provides a wide array of enzymes that enable processing of diverse dietary components. Because the primary diet of the porcupine, Erethizon dorsatum, is lignified plant material, we reasoned that the porcupine microbiome would be replete with enzymes required to degrade lignocellulose. Here, we report on the bacterial composition in the porcupine microbiome using 16S rRNA sequencing and bioinformatics analysis. We extended this analysis to the microbiomes of 20 additional mammals located in Shubenacadie Wildlife Park (Nova Scotia, Canada), enabling the comparison of bacterial diversity amongst three mammalian taxonomic orders (Rodentia, Carnivora, and Artiodactyla). 16S rRNA sequencing was validated using metagenomic shotgun sequencing on selected herbivores (porcupine, beaver) and carnivores (coyote, Arctic wolf). In the microbiome, functionality is more conserved than bacterial composition, thus we mined microbiome data sets to identify conserved microbial functions across species in each order. We measured the relative gene abundances for cellobiose phosphorylase, endoglucanase, and beta-glucosidase to evaluate the cellulose-degrading potential of select mammals. The porcupine and beaver had higher proportions of genes encoding cellulose-degrading enzymes than the Artic wolf and coyote. These findings provide further evidence that gut microbiome diversity and metabolic capacity are influenced by host diet.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.