Evidence map›Paper›PMID 29281479›Full record

ArticleCancer biology & therapy2018

Abscopal effect of radiation on bone metastases of breast cancer: A case report.

Henry Wc Leung, Shyh-Yau Wang, Huang Jin-Jhih, Agnes Lf Chan

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Cancer biology & therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Henry Wc Leunga Department of Radiation Oncology , An-Nan Hospital, China Medical University , No. 66, Sec. 2, Changhe Rd., Annan Dist., Tainan , Taiwan.
Shyh-Yau Wangb Department of Radiology , An Nan Hospital, China Medical University , No. 66, Sec. 2, Changhe Rd., Annan Dist., Tainan , Taiwan.
Huang Jin-Jhiha Department of Radiation Oncology , An-Nan Hospital, China Medical University , No. 66, Sec. 2, Changhe Rd., Annan Dist., Tainan , Taiwan.
Agnes Lf Chanc Department of Pharmacy , An Nan Hospital, China Medical University , No. 66, Sec. 2, Changhe Rd., Annan Dist., Tainan , Taiwan.
China Medical University · TWAn-Nan Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The abscopal effect is defined as the clearance of distant tumors after applying localized irradiation to a particular tumor site. It has been proposed that a mechanism for the abscopal effect might be the activation of the immune system, which leads to immunogenic tumor cell death. Here, we describe a woman with advanced breast cancer that received modified ablative radiation therapy that targeted her primary breast tumor. She experienced an apparent regression of metastatic mass in the thoracic spine. This case supported the hypothesis that the abscopal effect might be attributable to an activation of the systemic immune response.

Indexed as

Ablation TechniquesAgedBiomarkers, TumorBone NeoplasmsBreastBreast NeoplasmsCarcinoma, Ductal, BreastDose Fractionation, RadiationFemaleHumansTomography, X-Ray ComputedTreatment OutcomeBiomarkers, TumorAbscopal effectbone metastasesbreast cancer spontaneous regressionradiotherapy

Identifiers

PMID29281479
PMCPMC5790351
OpenAlexW2780311783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.