ArticleMicrobial biotechnology2018
Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement.
Article in Microbial biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
- Systematic design of auxotrophic strains and media conditions to probe metabolic functions in E. coli.PLoS computational biology · 2026Article
- Advances in genome-scale metabolic modeling of Bacillus subtilis.Biotechnology letters · 2026Review
- Molecular Strategies of Carbohydrate Binding to Intrinsically Disordered Regions in Bacterial Transcription Factors.International journal of molecular sciences · 2026Article
- Whole-Genome Sequencing and Analysis Reveals Plant Growth-Promoting Properties and Biocontrol Potential of theMicroorganisms · 2026Article
- Differential Assembly of Rhizosphere Microbiome and Metabolome in Rice with Contrasting Resistance to Blast Disease.Microorganisms · 2025Article
- Biodegradation mechanism of butralin by a newly isolatedRSC advances · 2025Article
- AJournal of bacteriology · 2025Article
- Characterization of a small non-coding RNA S612 inEngineering microbiology · 2025Article
- Physicochemical properties of plasma-activated water and associated antimicrobial activity against fungi and bacteria.Scientific reports · 2025Article
- Machine Learning-Based predictive model for adolescent metabolic syndrome: Utilizing data from NHANES 2007-2016.Scientific reports · 2025Article
- Unlocking the Potential ofFoods (Basel, Switzerland) · 2025Article
- Essential oils and their blends: mechanism of antibacterial activity and antibiofilm potential on food-grade maize starch packaging films.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Article
- A historical sequence deletion in a commonly usedMicrobiology (Reading, England) · 2024Article
- Control of asparagine homeostasis inJournal of bacteriology · 2024Article
- A historical sequence deletion in a commonly usedbioRxiv : the preprint server for biology · 2024Article
- Exploring overlooked growth-promoting mechanisms by plant-associated bacteria.Sustainable microbiology · 2024Review
- Giving a signal: how protein phosphorylation helps Bacillus navigate through different life stages.FEMS microbiology reviews · 2023Review
- A model industrial workhorse: Bacillus subtilis strain 168 and its genome after a quarter of a century.Microbial biotechnology · 2023Review
- Nanoantibiotic effect of carbon-based nanocomposites: epicentric on graphene, carbon nanotubes and fullerene composites: a review.3 Biotech · 2023Review
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Authors and funding
7 authors.
Funding
Abstract
Genome annotation is, nowadays, performed via automatic pipelines that cannot discriminate between right and wrong annotations. Given their importance in increasing the accuracy of the genome annotations of other organisms, it is critical that the annotations of model organisms reflect the current annotation gold standard. The genome of Bacillus subtilis strain 168 was sequenced twenty years ago. Using a combination of inductive, deductive and abductive reasoning, we present a unique, manually curated annotation, essentially based on experimental data. This reveals how this bacterium lives in a plant niche, while carrying a paleome operating system common to Firmicutes and Tenericutes. Dozens of new genomic objects and an extensive literature survey have been included for the sequence available at the INSDC (AccNum AL009126.3). We also propose an extension to Demerec's nomenclature rules that will help investigators connect to this type of curated annotation via the use of common gene names.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.