ArticleLasers in medical science2018
Photobiomodulation increases mitochondrial citrate synthase activity in rats submitted to aerobic training.
Article in Lasers in medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 21 citations in OpenAlex.
- Polarized or threshold training: is there a superior training intensity distribution to improve V̇OJournal of physiology and biochemistry · 2025Article
- The dose-effect response of combined red and infrared photobiomodulation on insulin resistance in skeletal muscle cells.Biochemistry and biophysics reports · 2024Article
- Promising improvement in infected Wound Healing in Type two Diabetic rats by Combined effects of conditioned medium of human adipose-derived stem cells plus Photobiomodulation.Laboratory animal research · 2023Article
- Effects of early exercise on cardiac function and lipid metabolism pathway in heart failure.Journal of cellular and molecular medicine · 2023Article
- Combined Use of Photobiomodulation and Curcumin-Loaded Iron Oxide Nanoparticles Significantly Improved Wound Healing in Diabetic Rats Compared to Either Treatment Alone.Journal of lasers in medical sciences · 2023Article
- Comparison between low, moderate, and high intensity aerobic training with equalized loads on biomarkers and performance in rats.Scientific reports · 2022Article
- Photobiomodulation intervention improves oxidative, inflammatory, and morphological parameters of skeletal muscle in cirrhotic Wistar rats.Lasers in medical science · 2022Article
- Photobiomodulation and Sports: Results of a Narrative Review.Life (Basel, Switzerland) · 2021Review
- Measurement of Physical Parameters and Development of a Light Emitting Diodes Device for Therapeutic Use.Journal of medical systems · 2020Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigated the effects of photobiomodulation by low-laser laser therapy (LLLT) on the activities of citrate synthase (CS) and lactate dehydrogenase (LDH) and the anaerobic threshold (AT) in rats submitted to treadmill exercise. Fifty-four rats were allocated into four groups: rest control (RCG), rest laser (RLG), exercise control (ECG), and exercise laser (ELG). The infrared LLLT was applied daily on the quadriceps, gluteus maximum, soleus, and tibialis anterior muscles. Muscle samples (soleus, tibialis anterior, and cardiac muscles) were removed 48 h after the last exercise session for spectrophotometric analysis of the CS and LDH. The CS activity (μmol/protein) in ELG (16.02 and 0.49) was significantly greater (P < 0.05) than RCG (2.34 and 0.24), RLG (6.25 and 0.17), and ECG (6.76 and 0.26) in the cardiac and soleus muscles, respectively. The LDH activity (in 1 Mm/protein) in soleus muscle was smaller (P < 0.05) for ELG (0.33) compared to ECG (0.97), RLG (0.79), and RCG (1.07). For cardiac muscle, the LDH activity was smaller (P < 0.05) in ELG (1.38) compared to ECG (1.91) and RCG (2.55). The ECG and ELG showed increases in the maximum speed and a shift of the AT to higher effort levels after the training period, but no differences occurred between the exercised groups. In conclusion, the aerobic treadmill training combined with LLLT promotes an increase of oxidative capacity in this rat model, mainly in muscles with greater aerobic capacity.
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