Evidence map›Paper›PMID 29280052›Full record

ArticleJournal of community genetics2018

Patient and provider perspectives on the development of personalized medicine: a mixed-methods approach.

Lauren Puryear, Natalie Downs, Andrea Nevedal, Eleanor T Lewis, Kelly E Ormond, Maria Bregendahl, Carlos J Suarez, Sean P David, Steven Charlap, Isabella Chu and 5 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of community genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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  9. Differences in Perception of Healthcare Management between Patients and Professionals.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Lauren PuryearDepartment of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
Natalie DownsDepartment of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
Andrea NevedalCenter for Innovation to Implementation, VA Palo Alto Health Care System, Livermore, CA, USA.
Eleanor T LewisCenter for Innovation to Implementation, VA Palo Alto Health Care System, Livermore, CA, USA.
Kelly E OrmondDepartment of Genetics and Stanford Center for Biomedical Ethics, Stanford University School of Medicine, Stanford, CA, USA.
Maria BregendahlDivision of Primary Care and Population Health, Stanford University School of Medicine, 1265 Welch Road, MC: 5475, Stanford, CA, 94305, USA.
Carlos J SuarezDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Sean P DavidDivision of Primary Care and Population Health, Stanford University School of Medicine, 1265 Welch Road, MC: 5475, Stanford, CA, 94305, USA.
Steven CharlapGeneYes, LLC, Palo Alto, CA, USA.
Isabella ChuCenter for Population Health Sciences, Stanford University, Stanford, CA, USA.
Steven M AschDivision of Primary Care and Population Health, Stanford University School of Medicine, 1265 Welch Road, MC: 5475, Stanford, CA, 94305, USA.
Neda PakdamanDivision of Primary Care and Population Health, Stanford University School of Medicine, 1265 Welch Road, MC: 5475, Stanford, CA, 94305, USA.
Sang-Ick ChangDivision of Primary Care and Population Health, Stanford University School of Medicine, 1265 Welch Road, MC: 5475, Stanford, CA, 94305, USA.
Mark R CullenCenter for Population Health Sciences, Stanford University, Stanford, CA, USA.
Latha PalaniappanDivision of Primary Care and Population Health, Stanford University School of Medicine, 1265 Welch Road, MC: 5475, Stanford, CA, 94305, USA. lathap@stanford.edu.
Stanford University · USCenter for Innovation · USVA Palo Alto Health Care System · US

Funding

Spectrum Stanford Center for clinical and Translational Research and EducationUL1TR001085 · NCATS · STANFORD UNIVERSITY · PI CULLEN, MARK RICHARD, GREENBERG, HARRY BERNARD · 2013 to 2017
$37.1M
NCATS NIH HHS UL1 TR001085Spectrum (Stanford Center for Clinical and Translational Research and Education) UL1 TR001085
6 · The paper itself

Abstract

While genetic testing gains adoption in specialty services such as oncology, neurology, and cardiology, use of genetic and genomic testing has yet to be adopted as widely in primary care. The purpose of this study is to identify and compare patient and primary care provider (PCP) expectations of genetics services in primary care. Patient and PCP perspectives were assessed through a mixed-method approach combining an online survey and semi-structured interviews in a primary care department of a large academic medical institution. A convenience sample of 100 adult primary care patients and 26 PCPs was gathered. The survey and interview questions focused on perceptions of genetic testing, experience with genetic testing, and expectations of genetic services in primary care. Patients felt that their PCP was knowledgeable about genetic testing and expected their PCP to be the first to recognize a need for genetic testing based on family history. Nonetheless, patients reported that PCPs rarely used family history information to discuss genetic risks or order testing. In contrast, PCPs felt uncertain about the clinical utility and scientific value of genetic testing. PCPs were concerned that genetic testing could cause anxiety, frustration, discrimination, and reduced insurability, and that there was unequal access to testing. PCPs described themselves as being "gatekeepers" to genetic testing but did not feel confident or have the desire to become experts in genetic testing. However, PCPs were open to increasing their working knowledge of genetic testing. Within this academic medical center, there is a gap between what patients expect and what primary care providers feel they are adequately prepared to provide in terms of genetic testing services.

Indexed as

GeneticsPatient-centered carePersonalized medicinePhysician decision supportPrimary care

Identifiers

PMID29280052
PMCPMC6002302
OpenAlexW2780769018

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.