Evidence map›Paper›PMID 29279943›Full record

Observational studyEuropean journal of nuclear medicine and molecular imaging2018

Assessment of alteration in liver

Thibault Salomon, Catherine Nganoa, Anne-Claire Gac, Christophe Fruchart, Gandhi Damaj, Nicolas Aide, Charline Lasnon

Abstract readObservational Study
In one paragraph

Observational study in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The use of a visual 4-point scoring scale improves the yield ofEuropean journal of nuclear medicine and molecular imaging · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Assessment of alteration in liverEuropean journal of nuclear medicine and molecular imaging · 2018
    Article
  11. The findings of 18World journal of nuclear medicine
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Thibault SalomonNuclear Medicine Department, Caen University Hospital, Caen, France.
Catherine NganoaNuclear Medicine Department, Caen University Hospital, Caen, France.
Anne-Claire GacHaematology Institute, Caen University Hospital, Caen, France.
Christophe FruchartHaematology Institute, François Baclesse Cancer Centre, Caen, France.
Gandhi DamajHaematology Institute, Caen University Hospital, Caen, France.
Nicolas AideNuclear Medicine Department, Caen University Hospital, Caen, France. aide-n@chu-caen.fr.ORCID 0000-0001-9207-0847
Charline LasnonINSERM 1086 ANTICIPE, Normandie University, Caen, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimOur aim was (1) to evaluate the prevalence of steatosis in lymphoma patients and its evolution during treatment; (2) to evaluate the impact of hepatic steatosis on

methodsOver a 1-year period, 358 PET scans from 227 patients [122 diffuse large B cell lymphoma (DLBCL), 57 Hodgkin lymphoma (HL) and 48 Follicular lymphoma (FL)] referred for baseline (n = 143), interim (n = 79) and end-of-treatment (EoT, n = 136) PET scans were reviewed. Steatosis was diagnosed on the unenhanced CT part of PET/CT examinations using a cut-off value of 42 Hounsfield units (HU). EARL-compliant SUL

resultsPrevalence of steatosis at baseline, interim and EoT PET was 15/143 (10.5%), 6/79 (7.6%) and 16/136 (11.8%), respectively (p = 0.62).Ten out of 27 steatotic patients (37.0%) displayed a steatotic liver on all examinations. Six patients (22.2%) had a disappearance of hepatic steatosis during their time-course of treatment. Only one patient developed steatosis during his course of treatment. Liver SUL

conclusionsSteatosis is actually a theoretical but not practical issue in most patients but should be recognised and corrected in appropriate cases, namely, for those patients scored DS4 with a percentage difference between the target lesion and the liver background lower than 30%.

Indexed as

Fatty LiverPositron Emission Tomography Computed TomographyAdolescentAdultAgedAged, 80 and overFemaleFluorodeoxyglucose F18HumansLiverLymphomaMaleMiddle AgedPositron-Emission TomographyRetrospective StudiesYoung AdultFluorodeoxyglucose F18Deauville scoreFDGLiverLymphomaPETSteatosis

Identifiers

PMID29279943
PMCPMC5915498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.